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NCT05014165 · ClinicalTrials.gov registry record
Backtracking Leukemia-Typical Somatic Mutations in Cord Blood
A clinical trial of Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia, sponsored by Children's Oncology Group.
- Recruiting
- Registry status
- 300
- Enrollment target
- 1
- Study location
NCT05014165 is a study of Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia that is actively recruiting participants, run by Children's Oncology Group. The registered enrollment target is 300 participants, above the 115-participant average among 306 other Acute Myeloid Leukemia trials with a reported enrollment target (161% higher). The trial reports 1 study location across 1 state.
The verdict
NCT05014165, a study of Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia, is actively recruiting participants, sponsored by Children's Oncology Group.
- RECRUITING
- Registry status
- 300 participants
- Enrollment target
- 1
- Study location
Study Summary
A comprehensive mechanistic and epidemiological study to obtain banked cord blood samples from consecutive childhood leukemia patients enrolled in the COG Project:EveryChild (APEC14B1) study. Will attempt to backtrack the initiating genomic alteration identified in the matched diagnostic leukemia sample and molecularly characterize pre-leukemic cells. The ultimate goal of this research is to pinpoint the cell of origin of leukemogenic alterations formed in utero, elucidating the etiology of these initiating mutations (as opposed to frank leukemia), and devising a test for circulating pre-leukemia that can be applied on a population-wide basis.
Conditions Studied
Interventions
- OTHER Questionnaire Administration
- OTHER Cord blood Sample Collection
- OTHER Case identification and recruitment
Study Locations (1)
Minnesota
- University of Minnesota/Masonic Cancer Center - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2021-08-25 |
| Est. Completion | 2026-09-30 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05014165
The ClinicalTrials.gov registry entry for NCT05014165 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 115-participant average among 306 other Acute Myeloid Leukemia trials with a reported enrollment target (161% higher). The listed sponsor is Children's Oncology Group, which has 342 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Acute Myeloid Leukemia appearing as the primary indexed condition, and to 3 interventions - of which Questionnaire Administration is the first listed.
NCT05014165 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.
Frequently Asked Questions
What is clinical trial NCT05014165 about?
NCT05014165 is a clinical study titled "Backtracking Leukemia-Typical Somatic Mutations in Cord Blood". A comprehensive mechanistic and epidemiological study to obtain banked cord blood samples from consecutive childhood leukemia patients enrolled in the COG Project:EveryChild (APEC14B1) study. Will attempt to backtrack the initiating genomic alteration identified in the matched diagnostic leukemia sa...
What is the current status of trial NCT05014165?
This trial is currently recruiting. The enrollment target is 300 participants. The study started on 2021-08-25. Estimated completion is 2026-09-30.
What conditions does trial NCT05014165 study?
This clinical trial studies the following conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia.
What interventions are being tested in trial NCT05014165?
The interventions under investigation include: Questionnaire Administration (OTHER), Cord blood Sample Collection (OTHER), Case identification and recruitment (OTHER).
Who is sponsoring clinical trial NCT05014165?
This trial is sponsored by Children's Oncology Group, which has 342 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05014165 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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