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NCT05013502 · ClinicalTrials.gov registry record · Phase 1

Empagliflozin in Diuretic Refractory Ascites

A Phase 1 study, sponsored by Stanford University.

Completed
Registry status
Phase 1
Development phase
14
Enrollment target

NCT05013502: Completed Phase 1 study, sponsored by Stanford University.

NCT05013502 is a Phase 1 study that has completed, run by Stanford University. The registered enrollment target is 14 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT05013502, a Phase 1 study, has completed, sponsored by Stanford University.

COMPLETED
Registry status
Phase 1
Development phase
14 participants
Enrollment target

Study Summary

Ascites is the most frequent complication of liver cirrhosis and results in increased morbidity and mortality but current medical management options are limited. Here, the investigators will conduct an interventional single-arm pilot clinical trial toevaluate the feasibility of empagliflozin in managing diuretic-resistant ascites in patients with decompensated cirrhosis. This single site, open label pilot study will enroll participants with decompensated cirrhosis at a single site. Participants will receive empagliflozin 10mg oral tablets once daily for 12 weeks with monitoring for safety and adverse events.

Primary Outcome

Retention rate and completion of trial activities through 12 weeks

Interventions

  • DRUG Empagliflozin 10 MG

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2021-11-15
Est. Completion 2023-06-30
Phase Phase 1
Stanford University

1,744 total trials

What the finished NCT05013502 record still lists

NCT05013502 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower).

The record links to 0 conditions, and to 1 intervention - of which Empagliflozin 10 MG is the first listed.

NCT05013502 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05013502 about?

NCT05013502 is a clinical study titled "Empagliflozin in Diuretic Refractory Ascites". Ascites is the most frequent complication of liver cirrhosis and results in increased morbidity and mortality but current medical management options are limited. Here, the investigators will conduct an interventional single-arm pilot clinical trial toevaluate the feasibility of empagliflozin in mana...

What is the current status of trial NCT05013502?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 14 participants. The study started on 2021-11-15. Estimated completion is 2023-06-30.

What interventions are being tested in trial NCT05013502?

The interventions under investigation include: Empagliflozin 10 MG (DRUG).

Who is sponsoring clinical trial NCT05013502?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05013502's enrollment target sits among peer trials

14 1844th of 2000 higher than 154 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05013502, the US trial registry maintained by the National Library of Medicine. NCT05013502 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.