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NCT04999527 · ClinicalTrials.gov registry record · Phase 1
Study to Evaluate the Safety, Tolerability, PK and PD of DISC-0974 in Healthy Subjects
A Phase 1 study, sponsored by Disc Medicine.
- Completed
- Registry status
- Phase 1
- Development phase
- 42
- Enrollment target
NCT04999527: Completed Phase 1 study, sponsored by Disc Medicine.
NCT04999527 is a Phase 1 study that has completed, run by Disc Medicine. The registered enrollment target is 42 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (30% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04999527, a Phase 1 study, has completed, sponsored by Disc Medicine.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 42 participants
- Enrollment target
Study Summary
This Phase 1 study of DISC-0974 will assess the safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult healthy volunteers.
Interventions
- DRUG Placebo
- DRUG DISC-0974
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2021-08-10 |
| Est. Completion | 2022-06-30 |
| Phase | Phase 1 |
What the finished NCT04999527 record still lists
NCT04999527 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (30% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04999527 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04999527 about?
NCT04999527 is a clinical study titled "Study to Evaluate the Safety, Tolerability, PK and PD of DISC-0974 in Healthy Subjects". This Phase 1 study of DISC-0974 will assess the safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult healthy volunteers.
What is the current status of trial NCT04999527?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 42 participants. The study started on 2021-08-10. Estimated completion is 2022-06-30.
What interventions are being tested in trial NCT04999527?
The interventions under investigation include: Placebo (DRUG), DISC-0974 (DRUG).
Who is sponsoring clinical trial NCT04999527?
This trial is sponsored by Disc Medicine, which has 9 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04999527's enrollment target sits among peer trials
42 1105th of 2000 higher than 876 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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