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NCT04993339 · ClinicalTrials.gov registry record · Phase 3
Clinical Outcomes of ACL Reconstruction Augmented by an Injectable Osteoconductive/Osteoinductive Compound
A Phase 3 study of ACL Injury, sponsored by University of Miami.
- Completed
- Registry status
- Phase 3
- Development phase
- 26
- Enrollment target
- 1
- Study location
NCT04993339: Completed Phase 3 study of ACL Injury, sponsored by University of Miami.
NCT04993339 is a Phase 3 study of ACL Injury that has completed, run by University of Miami. The registered enrollment target is 26 participants, below the 502-participant average among 12 other ACL Injury trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04993339, a Phase 3 study of ACL Injury, has completed, sponsored by University of Miami.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 26 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to determine whether the use of injectable osteoinductive/osteoconductive compounds (OOC) during Anterior Cruciate Ligament (ACL) reconstructive surgery, combined with an accelerated rehabilitation protocol (ARP) provides clinical outcomes superior to those attained via traditional ACL reconstruction and delayed rehabilitation protocols.
Primary Outcome
Number of participants will be classified with having femoral and tibial tunnel expansion as: * minimal expansion (\<1mm) * mild expansion (\<5mm) * moderate expansion (5-10mm) * large expansion (\>10mm) as measured via Magnetic Resonance Imaging (MRI)
Conditions Studied
Interventions
- DRUG OOC
Study Locations (1)
Florida
- University of Miami - Coral Gables
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2016-10-24 |
| Est. Completion | 2020-02-20 |
| Phase | Phase 3 |
What the finished NCT04993339 record still lists
NCT04993339 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 502-participant average among 12 other ACL Injury trials with a reported enrollment target (95% lower).
The record links to 1 condition, with ACL Injury appearing as the primary indexed condition, and to 1 intervention - of which OOC is the first listed.
NCT04993339 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT04993339 about?
NCT04993339 is a clinical study titled "Clinical Outcomes of ACL Reconstruction Augmented by an Injectable Osteoconductive/Osteoinductive Compound". The goal of this study is to determine whether the use of injectable osteoinductive/osteoconductive compounds (OOC) during Anterior Cruciate Ligament (ACL) reconstructive surgery, combined with an accelerated rehabilitation protocol (ARP) provides clinical outcomes superior to those attained via tra...
What is the current status of trial NCT04993339?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 26 participants. The study started on 2016-10-24. Estimated completion is 2020-02-20.
What conditions does trial NCT04993339 study?
This clinical trial studies the following conditions: ACL Injury.
What interventions are being tested in trial NCT04993339?
The interventions under investigation include: OOC (DRUG).
Who is sponsoring clinical trial NCT04993339?
This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04993339 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for ACL Injury
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04993339's enrollment target sits among peer trials
26 12th of 12 higher than 1 of 12 other ACL Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other ACL Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Michigan Split-belt Treadmill Training Program to Improve Long-Term Knee Biomechanics After ACL Reconstruction
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Concentrated Bone Marrow Aspirate in Revision ACL Reconstruction
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MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial)
RECRUITING · Early Phase 1
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Michigan Split-belt Treadmill Training Program to Improve Acute Knee Biomechanics After ACL Reconstruction
RECRUITING · NA
-
Baseline ACL Injury Risk Screening and Normative Data
RECRUITING
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