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NCT04991974 · ClinicalTrials.gov registry record · Phase 2
Opioid Use Disorder Treatment Linkage at Strategic Touchpoints Using Buprenorphine
A Phase 2 study, sponsored by Friends Research Institute.
- Completed
- Registry status
- Phase 2
- Development phase
- 373
- Enrollment target
NCT04991974: Completed Phase 2 study, sponsored by Friends Research Institute.
NCT04991974 is a Phase 2 study that has completed, run by Friends Research Institute. The registered enrollment target is 373 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (180% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04991974, a Phase 2 study, has completed, sponsored by Friends Research Institute.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 373 participants
- Enrollment target
Study Summary
This study will examine the effectiveness of opioid use disorder (OUD) treatment linkage strategies for patients identified at sexual health clinics and through community outreach and referrals. This 3-arm RCT will compare Usual Care vs. Patient Navigation vs. Patient Navigation + Buprenorphine Initiation (UC vs. PN vs. PN+BUP).
Primary Outcome
The primary outcome for the trial is OUD treatment entry by 1 month post-enrollment, defined as admission to a buprenorphine provider (either office-based care or a specialty OUD program), or other licensed OUD treatment program (e.g., methadone, medical detox followed by behavioral treatment).
Interventions
- DRUG Buprenorphine
- BEHAVIORAL Patient Navigation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 373 participants |
| Start Date | 2021-09-17 |
| Est. Completion | 2026-01-31 |
| Phase | Phase 2 |
What the finished NCT04991974 record still lists
NCT04991974 is an interventional study that assigns participants to a tested intervention. The registered 373 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (180% higher).
The record links to 0 conditions, and to 2 interventions - of which Buprenorphine is the first listed.
NCT04991974 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04991974 about?
NCT04991974 is a clinical study titled "Opioid Use Disorder Treatment Linkage at Strategic Touchpoints Using Buprenorphine". This study will examine the effectiveness of opioid use disorder (OUD) treatment linkage strategies for patients identified at sexual health clinics and through community outreach and referrals. This 3-arm RCT will compare Usual Care vs. Patient Navigation vs. Patient Navigation + Buprenorphine Init...
What is the current status of trial NCT04991974?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 373 participants. The study started on 2021-09-17. Estimated completion is 2026-01-31.
What interventions are being tested in trial NCT04991974?
The interventions under investigation include: Buprenorphine (DRUG), Patient Navigation (BEHAVIORAL).
Who is sponsoring clinical trial NCT04991974?
This trial is sponsored by Friends Research Institute, which has 41 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04991974's enrollment target sits among peer trials
373 118th of 2000 higher than 1,883 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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