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NCT04982406 · ClinicalTrials.gov registry record

Transcatheter Aortic Valve Replacement (TAVR) Effects on Cardiac Conduction System

A clinical trial, sponsored by Beth Israel Deaconess Medical Center.

Completed
Registry status
409
Enrollment target

NCT04982406 is a clinical trial that has completed, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 409 participants.

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The verdict

NCT04982406 has completed, sponsored by Beth Israel Deaconess Medical Center.

COMPLETED
Registry status
409 participants
Enrollment target

Study Summary

This is a prospective observational study, the purpose of which is to: 1. Characterize response of the AV conduction system to TAVR with various prostheses by recording continuous His bundle electrograms during valve placement. 2. Correlate preprocedure ECG features with changes in AV nodal and infranodal conduction during placement of the valve prosthesis. 3. Correlate changes in AV nodal and infranodal conduction during the procedure with risk of developing AV conduction block after TAVR. 4. Assess the contribution of stressing the conduction system by atrial pacing prior to and following TAVR to prediction of postprocedural heart block. Assess the correlation between new onset bundle branch block, site and degree of conduction block or delay and subsequent development of high-grade or complete AV block.

Interventions

  • DEVICE Transcatheter aortic valve replacement

Trial Details

FieldValue
Enrollment Target 409 participants
Start Date 2021-05-18
Est. Completion 2025-01-21

What the Registry Record Tells You About NCT04982406

The ClinicalTrials.gov registry entry for NCT04982406 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 409 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Beth Israel Deaconess Medical Center, which has 488 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Transcatheter aortic valve replacement is the first listed.

NCT04982406 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04982406 about?

NCT04982406 is a clinical study titled "Transcatheter Aortic Valve Replacement (TAVR) Effects on Cardiac Conduction System". This is a prospective observational study, the purpose of which is to: 1. Characterize response of the AV conduction system to TAVR with various prostheses by recording continuous His bundle electrograms during valve placement. 2. Correlate preprocedure ECG features with changes in AV nodal and inf...

What is the current status of trial NCT04982406?

This trial is currently completed. The enrollment target is 409 participants. The study started on 2021-05-18. Estimated completion is 2025-01-21.

What interventions are being tested in trial NCT04982406?

The interventions under investigation include: Transcatheter aortic valve replacement (DEVICE).

Who is sponsoring clinical trial NCT04982406?

This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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