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NCT04967222 · ClinicalTrials.gov registry record · NA
Cognitive Reappraisal Training for Borderline Personality
A NA study, sponsored by Icahn School of Medicine at Mount Sinai.
- Completed
- Registry status
- NA
- Development phase
- 60
- Enrollment target
NCT04967222: Completed NA study, sponsored by Icahn School of Medicine at Mount Sinai.
NCT04967222 is a NA study that has completed, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 60 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04967222, a NA study, has completed, sponsored by Icahn School of Medicine at Mount Sinai.
- COMPLETED
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
Study Summary
Previous work by the study group convinced the study team to pursue development of focused cognitive reappraisal training as a novel approach to treatment of BPD, either as stand-alone treatment or in concert with evidence-based treatments of BPD. The present proposal aims to refine and test a proposed clinical intervention for BPD patients, training in reappraisal-by-distancing, in terms of its ability to influence hypothesized neural and behavioral targets and, once that is established, to demonstrate its ability improve clinically relevant outcome measures.
Primary Outcome
BOLD signal change in Picture Induced Negative Emotion Signature (PINES) network activity that includes the amygdala, insula, and other regions by measuring neural activation using fMRI.
Interventions
- BEHAVIORAL Cognitive Reappraisal by Distancing
- BEHAVIORAL Control Downregulate Condition
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2021-12-01 |
| Est. Completion | 2024-06-03 |
| Phase | NA |
What the finished NCT04967222 record still lists
NCT04967222 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Cognitive Reappraisal by Distancing is the first listed.
NCT04967222 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04967222 about?
NCT04967222 is a clinical study titled "Cognitive Reappraisal Training for Borderline Personality". Previous work by the study group convinced the study team to pursue development of focused cognitive reappraisal training as a novel approach to treatment of BPD, either as stand-alone treatment or in concert with evidence-based treatments of BPD. The present proposal aims to refine and test a propo...
What is the current status of trial NCT04967222?
This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2021-12-01. Estimated completion is 2024-06-03.
What interventions are being tested in trial NCT04967222?
The interventions under investigation include: Cognitive Reappraisal by Distancing (BEHAVIORAL), Control Downregulate Condition (BEHAVIORAL).
Who is sponsoring clinical trial NCT04967222?
This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04967222's enrollment target sits among peer trials
60 1164th of 2000 higher than 745 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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