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NCT04960579 · ClinicalTrials.gov registry record · Phase 1
P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma
A Phase 1 study of Multiple Myeloma, sponsored by Poseida Therapeutics.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 275
- Enrollment target
- 20
- Study locations
NCT04960579: Recruiting Phase 1 study of Multiple Myeloma, sponsored by Poseida Therapeutics.
NCT04960579 is a Phase 1 study of Multiple Myeloma that is actively recruiting participants, run by Poseida Therapeutics. The registered enrollment target is 275 participants, below the 546-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (50% lower). The trial reports 20 study locations across 15 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04960579, a Phase 1 study of Multiple Myeloma, is actively recruiting participants, sponsored by Poseida Therapeutics.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 275 participants
- Enrollment target
- 20
- Study locations
Study Summary
Phase 1 study comprised of open-label, dose escalation, multiple cohorts of P-BCMA-ALLO1 allogeneic T stem cell memory (Tscm) CAR-T cells in subjects with relapsed / refractory Multiple Myeloma (RRMM).
Primary Outcome
Rate of dose limiting toxicities (DLT)
Conditions Studied
Interventions
- DRUG Rimiducid
- DRUG Methotrexate
- BIOLOGICAL P-BCMA-ALLO1 CAR-T cells
Study Locations (20)
California
- University of California San Diego - San Diego
- University of California San Francisco - San Francisco
Georgia
- Emory University - Atlanta
- Blood Marrow and Transplant Group of Georgia - Atlanta
Illinois
- City of Hope - Chicago
- Advocate Aurora Health - Park Ridge
New York
- Roswell Park Comprehensive Cancer Center - Buffalo
- Mount Sinai - New York
Ohio
- University of Cincinnati - Cincinnati
- Cleveland Clinic - Cleveland
Arizona
- City of Hope - Goodyear
Iowa
- University of Iowa - Iowa City
Kansas
- University of Kansas Medical Center - Kansas City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 275 participants |
| Start Date | 2022-05-05 |
| Est. Completion | 2042-03 |
| Phase | Phase 1 |
What NCT04960579 shows while recruiting
NCT04960579 is an interventional study that assigns participants to a tested intervention. The registered 275 participants enrollment target is mid-sized for trials with a published cap, below the 546-participant average among 438 other Multiple Myeloma trials with a reported enrollment target (50% lower).
The record links to 1 condition, with Multiple Myeloma appearing as the primary indexed condition, and to 3 interventions - of which Rimiducid is the first listed.
NCT04960579 names 20 study sites across 15 states, led by California, Georgia, Illinois.
Frequently Asked Questions
What is clinical trial NCT04960579 about?
NCT04960579 is a clinical study titled "P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma". Phase 1 study comprised of open-label, dose escalation, multiple cohorts of P-BCMA-ALLO1 allogeneic T stem cell memory (Tscm) CAR-T cells in subjects with relapsed / refractory Multiple Myeloma (RRMM).
What is the current status of trial NCT04960579?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 275 participants. The study started on 2022-05-05. Estimated completion is 2042-03.
What conditions does trial NCT04960579 study?
This clinical trial studies the following conditions: Multiple Myeloma.
What interventions are being tested in trial NCT04960579?
The interventions under investigation include: Rimiducid (DRUG), Methotrexate (DRUG), P-BCMA-ALLO1 CAR-T cells (BIOLOGICAL).
Who is sponsoring clinical trial NCT04960579?
This trial is sponsored by Poseida Therapeutics, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04960579 being conducted?
This trial has 20 study locations across Arizona, California, Georgia, Illinois, Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Multiple Myeloma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04960579's enrollment target sits among peer trials
275 83rd of 438 higher than 356 of 438 other Multiple Myeloma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Multiple Myeloma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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