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NCT04944862 · ClinicalTrials.gov registry record · Phase 1
A Study of CDX-0159 in Patients With Prurigo Nodularis
A Phase 1 study, sponsored by Celldex Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
NCT04944862: Completed Phase 1 study, sponsored by Celldex Therapeutics.
NCT04944862 is a Phase 1 study that has completed, run by Celldex Therapeutics. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04944862, a Phase 1 study, has completed, sponsored by Celldex Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
Study Summary
The purpose of the study is to explore the safety, clinical effect, pharmacodynamics, and pharmacokinetics of CDX-0159 (barzolvolimab) in patients with Prurigo Nodularis.
Primary Outcome
Safety and tolerability of multiple dose levels of CDX-0159 as determined by drug related adverse events
Interventions
- DRUG Normal saline
- BIOLOGICAL CDX-0159
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2021-11-08 |
| Est. Completion | 2023-07-31 |
| Phase | Phase 1 |
What the finished NCT04944862 record still lists
NCT04944862 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).
The record links to 0 conditions, and to 2 interventions - of which Normal saline is the first listed.
NCT04944862 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04944862 about?
NCT04944862 is a clinical study titled "A Study of CDX-0159 in Patients With Prurigo Nodularis". The purpose of the study is to explore the safety, clinical effect, pharmacodynamics, and pharmacokinetics of CDX-0159 (barzolvolimab) in patients with Prurigo Nodularis.
What is the current status of trial NCT04944862?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2021-11-08. Estimated completion is 2023-07-31.
What interventions are being tested in trial NCT04944862?
The interventions under investigation include: Normal saline (DRUG), CDX-0159 (BIOLOGICAL).
Who is sponsoring clinical trial NCT04944862?
This trial is sponsored by Celldex Therapeutics, which has 42 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04944862's enrollment target sits among peer trials
24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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