Celldex Therapeutics

14 total trials 3 currently recruiting 6 completed

Trial Pipeline

RECRUITING Phase 1

A Study of CDX-622 in Participants With Mild to Moderate Asthma

NCT07330778

RECRUITING Phase 3

A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)

NCT07266402

RECRUITING Phase 3

Long-term Efficacy and Safety Extension (LTE) Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria

NCT07256392

ACTIVE NOT RECRUITING Phase 2

A Study of Barzolvolimab in Patients With Atopic Dermatitis

NCT06727552

ACTIVE NOT RECRUITING Phase 1

A Phase I Study of CDX-622

NCT06650761

ACTIVE NOT RECRUITING Phase 3

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)

NCT06455202

ACTIVE NOT RECRUITING Phase 3

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria

NCT06445023

ACTIVE NOT RECRUITING Phase 2

A Study of Barzolvolimab in Patients With Prurigo Nodularis

NCT06366750

COMPLETED Phase 2

A Study of CDX-0159 in Patients With Chronic Inducible Urticaria

NCT05405660

COMPLETED Phase 1

A Phase 1 Study of CDX-0159

NCT04146129

COMPLETED Phase 1

A Study to Evaluate the Safety and Pharmacokinetics of CDX-0158 in Adult Patients With Advanced Solid Tumors

NCT02642016

COMPLETED Phase 2

Study of Glembatumumab Vedotin (CDX-011) in Patients With Metastatic, gpNMB Over-Expressing, Triple Negative Breast Cancer

NCT01997333

COMPLETED Phase 2

A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma

NCT01498328

COMPLETED Phase 1

A Study of CDX-1307, in Patients With Incurable Breast, Colorectal, Pancreatic, Ovarian or Bladder Cancer (CDX 1307-01)

NCT00709462

What the Pipeline for Celldex Therapeutics Shows

According to the ClinicalTrials.gov registry, Celldex Therapeutics is linked to 14 US clinical trials across every stage of research activity. Of those, 3 studies are currently recruiting — about 21% of the sponsor's indexed portfolio — and 6 are already marked complete, representing roughly 43% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for Celldex Therapeutics reports 4 late-stage studies (Phase 3 and Phase 4 combined) and 10 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for Celldex Therapeutics is Chronic Spontaneous Urticaria with 3 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial