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NCT04936529 · ClinicalTrials.gov registry record · Phase 2

A Study of a Vaccine in Combination With β-glucan and GM-CSF in People With Neuroblastoma

A Phase 2 study of Neuroblastoma, sponsored by Memorial Sloan Kettering Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
286
Enrollment target
1
Study location

NCT04936529 is a Phase 2 study of Neuroblastoma that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 286 participants, above the 236-participant average among 94 other Neuroblastoma trials with a reported enrollment target (21% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT04936529, a Phase 2 study of Neuroblastoma, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
286 participants
Enrollment target
1
Study location

Study Summary

The purpose of the study is to explore the combination of a bivalent vaccine, a sugar called beta-glucan (β-glucan), and a protein called granulocyte-macrophage colony stimulating factor (GM-CSF) as an effective treatment for people with high-risk neuroblastoma that is in complete remission. The combination may be effective because the different parts of the treatment work to strengthen the immune system's response against cancer cells in different ways.

Conditions Studied

Interventions

  • DIETARY_SUPPLEMENT β-glucan
  • DRUG GM-CSF
  • BIOLOGICAL OPT-821

Study Locations (1)

New York

  • Memorial Sloan Kettering Cancer Center - New York

Trial Details

FieldValue
Enrollment Target 286 participants
Start Date 2021-08-02
Est. Completion 2026-06-15
Phase Phase 2

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT04936529

The ClinicalTrials.gov registry entry for NCT04936529 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 286 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 236-participant average among 94 other Neuroblastoma trials with a reported enrollment target (21% higher). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Neuroblastoma appearing as the primary indexed condition, and to 3 interventions - of which β-glucan is the first listed.

NCT04936529 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT04936529 about?

NCT04936529 is a clinical study titled "A Study of a Vaccine in Combination With β-glucan and GM-CSF in People With Neuroblastoma". The purpose of the study is to explore the combination of a bivalent vaccine, a sugar called beta-glucan (β-glucan), and a protein called granulocyte-macrophage colony stimulating factor (GM-CSF) as an effective treatment for people with high-risk neuroblastoma that is in complete remission. The com...

What is the current status of trial NCT04936529?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 286 participants. The study started on 2021-08-02. Estimated completion is 2026-06-15.

What conditions does trial NCT04936529 study?

This clinical trial studies the following conditions: Neuroblastoma.

What interventions are being tested in trial NCT04936529?

The interventions under investigation include: β-glucan (DIETARY_SUPPLEMENT), GM-CSF (DRUG), OPT-821 (BIOLOGICAL).

Who is sponsoring clinical trial NCT04936529?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04936529 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.