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NCT04926818 · ClinicalTrials.gov registry record · Phase 3
Efficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple Sclerosis
A Phase 3 study of Multiple Sclerosis, MS, sponsored by Novartis Pharmaceuticals.
- Active
- Registry status
- Phase 3
- Development phase
- 129
- Enrollment target
- 20
- Study locations
NCT04926818 is a Phase 3 study of Multiple Sclerosis, MS that is active but no longer recruiting, run by Novartis Pharmaceuticals. The registered enrollment target is 129 participants, above the 49-participant average among 7 other Multiple Sclerosis, MS trials with a reported enrollment target (163% higher). The trial reports 20 study locations across 13 states.
The verdict
NCT04926818, a Phase 3 study of Multiple Sclerosis, MS, is active but no longer recruiting, sponsored by Novartis Pharmaceuticals.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 129 participants
- Enrollment target
- 20
- Study locations
Study Summary
Efficacy and safety of ofatumumab and siponimod compared to fingolimod in pediatric patients with multiple sclerosis
Conditions Studied
Interventions
- DRUG Fingolimod
- DRUG Siponimod
- DRUG Ofatumumab
- OTHER Fingolimod placebo
- OTHER Siponimod placebo
Study Locations (20)
Other
- Novartis Investigative Site - CABA
- Novartis Investigative Site - Vienna
- Novartis Investigative Site - Esneux
- Novartis Investigative Site - Ghent
- Novartis Investigative Site - Zagreb
- Novartis Investigative Site - Tallinn
- Novartis Investigative Site - Le Kremlin-Bicêtre
Quebec
- Novartis Investigative Site - Montreal
- Novartis Investigative Site - Montreal
Arkansas
- Arkansas Childrens Hosp Rsch Inst - Little Rock
California
- Childrens Hospital Los Angeles - Los Angeles
District of Columbia
- Childrens National Medical Center - Washington D.C.
Florida
- Axiom Clinical Research of Florida - Tampa
Pennsylvania
- Childrens Hospital of Philadelphia - Philadelphia
Wisconsin
- Medical College of Wisconsin - Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 129 participants |
| Start Date | 2021-10-05 |
| Est. Completion | 2031-03-06 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04926818
The ClinicalTrials.gov registry entry for NCT04926818 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 129 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 49-participant average among 7 other Multiple Sclerosis, MS trials with a reported enrollment target (163% higher). The listed sponsor is Novartis Pharmaceuticals, which has 1,375 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Multiple Sclerosis, MS appearing as the primary indexed condition, and to 5 interventions - of which Fingolimod is the first listed.
NCT04926818 reports 20 study locations spanning 13 distinct geographic areas - top geographies include Other, Quebec, Arkansas.
Frequently Asked Questions
What is clinical trial NCT04926818 about?
NCT04926818 is a clinical study titled "Efficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple Sclerosis". Efficacy and safety of ofatumumab and siponimod compared to fingolimod in pediatric patients with multiple sclerosis
What is the current status of trial NCT04926818?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 129 participants. The study started on 2021-10-05. Estimated completion is 2031-03-06.
What conditions does trial NCT04926818 study?
This clinical trial studies the following conditions: Multiple Sclerosis, MS.
What interventions are being tested in trial NCT04926818?
The interventions under investigation include: Fingolimod (DRUG), Siponimod (DRUG), Ofatumumab (DRUG), Fingolimod placebo (OTHER), Siponimod placebo (OTHER).
Who is sponsoring clinical trial NCT04926818?
This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04926818 being conducted?
This trial has 20 study locations across Arkansas, California, District of Columbia, Florida, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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