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NCT04883528 · ClinicalTrials.gov registry record · Phase 1
Protecting With ARNI Against Cardiac Consequences of Coronavirus Disease 2019
A Phase 1 study, sponsored by Duke University.
- Completed
- Registry status
- Phase 1
- Development phase
- 42
- Enrollment target
NCT04883528: Completed Phase 1 study, sponsored by Duke University.
NCT04883528 is a Phase 1 study that has completed, run by Duke University. The registered enrollment target is 42 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (30% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04883528, a Phase 1 study, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 42 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the effect of sacubitril/valsartan versus placebo on markers of cardiac injury, structure, and function among patients who recovered from acute COVID-19 infection.
Primary Outcome
An elevated level of troponin T on the high-sensitivity cardiac troponin test indicates heart muscle damage or a heart attack.
Interventions
- DRUG Placebo
- DRUG Sacubitril / Valsartan Oral Tablet [Entresto]
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2021-08-06 |
| Est. Completion | 2023-06-13 |
| Phase | Phase 1 |
What the finished NCT04883528 record still lists
NCT04883528 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (30% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04883528 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04883528 about?
NCT04883528 is a clinical study titled "Protecting With ARNI Against Cardiac Consequences of Coronavirus Disease 2019". The purpose of this study is to determine the effect of sacubitril/valsartan versus placebo on markers of cardiac injury, structure, and function among patients who recovered from acute COVID-19 infection.
What is the current status of trial NCT04883528?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 42 participants. The study started on 2021-08-06. Estimated completion is 2023-06-13.
What interventions are being tested in trial NCT04883528?
The interventions under investigation include: Placebo (DRUG), Sacubitril / Valsartan Oral Tablet [Entresto] (DRUG).
Who is sponsoring clinical trial NCT04883528?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04883528's enrollment target sits among peer trials
42 1105th of 2000 higher than 876 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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