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NCT04880538 · ClinicalTrials.gov registry record
Enteric Neural Precursor Cells (ENPC) in the Human Gut
A clinical trial of Gastrointestinal Dysmotility, sponsored by Johns Hopkins University.
- Completed
- Registry status
- 5
- Enrollment target
- 1
- Study location
NCT04880538: Completed study of Gastrointestinal Dysmotility, sponsored by Johns Hopkins University.
NCT04880538 is a study of Gastrointestinal Dysmotility that has completed, run by Johns Hopkins University. The registered enrollment target is 5 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04880538, a study of Gastrointestinal Dysmotility, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- 5 participants
- Enrollment target
- 1
- Study location
Study Summary
The study aim is to acquire human tissues to (a) understand the structure and organization of the human Enteric Nervous System; (b) perform a molecular transcriptomic profile of individual cells residing in the human gut; (c) study the turnover rates of individual cell types by Fluorescence-activated cell sorting-aided C14 dating of cells; and finally (d) culture the human gut-derived cells characterize the human adult enteric neural stem cell and study its potential for Neuro-glial differentiation. This study will advance our knowledge of the the cellular and molecular correlates of changes in the Enteric Nervous System that are associated with disorders of motility.
Primary Outcome
Presence or absence of antibodies (including but not limited to) specific to Nestin, p75 neurotrophin receptor, pan-neuronal antibodies, pan-glial antibodies, antibodies against Interstitial Cells of Cajal.
Conditions Studied
Interventions
- PROCEDURE Endoscopic procedure
Study Locations (1)
Maryland
- Johns Hopkins Bayview Medical Center - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2021-04-26 |
| Est. Completion | 2023-09-11 |
What the finished NCT04880538 record still lists
NCT04880538 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 5 participants, a relatively small participant target.
The record links to 1 condition, with Gastrointestinal Dysmotility appearing as the primary indexed condition, and to 1 intervention - of which Endoscopic procedure is the first listed.
NCT04880538 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT04880538 about?
NCT04880538 is a clinical study titled "Enteric Neural Precursor Cells (ENPC) in the Human Gut". The study aim is to acquire human tissues to (a) understand the structure and organization of the human Enteric Nervous System; (b) perform a molecular transcriptomic profile of individual cells residing in the human gut; (c) study the turnover rates of individual cell types by Fluorescence-activate...
What is the current status of trial NCT04880538?
This trial is currently completed. The enrollment target is 5 participants. The study started on 2021-04-26. Estimated completion is 2023-09-11.
What conditions does trial NCT04880538 study?
This clinical trial studies the following conditions: Gastrointestinal Dysmotility.
What interventions are being tested in trial NCT04880538?
The interventions under investigation include: Endoscopic procedure (PROCEDURE).
Who is sponsoring clinical trial NCT04880538?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04880538 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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