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NCT04872439 · ClinicalTrials.gov registry record
Novel Antineuronal Antibodies in Gastrointestinal Motility Disorders
A clinical trial of Autoimmune Gastrointestinal Dysmotility, sponsored by Johns Hopkins University.
- Active
- Registry status
- 300
- Enrollment target
- 1
- Study location
NCT04872439 is a study of Autoimmune Gastrointestinal Dysmotility that is active but no longer recruiting, run by Johns Hopkins University. The registered enrollment target is 300 participants. The trial reports 1 study location across 1 state.
The verdict
NCT04872439, a study of Autoimmune Gastrointestinal Dysmotility, is active but no longer recruiting, sponsored by Johns Hopkins University.
- ACTIVE NOT RECRUITING
- Registry status
- 300 participants
- Enrollment target
- 1
- Study location
Study Summary
Gastrointestinal motility disorders represent a heterogeneous group of neuromuscular diseases of the enteric nervous systems. While autoimmune neuromuscular diseases of the central nervous system (CNS) are well described, the role of autoimmunity in enteric nervous system (ENS) has been less studied. Approximately 10% of patients with unexplained gastrointestinal dysmotility diseases have positive serum autoantibodies to peripheral nervous system proteins, suggesting an autoimmune mechanism targeting the enteric nervous system. The investigator's aim is to identify novel anti neuronal antibodies that contribute to autoimmune gastrointestinal motility disorders by analyzing the serum of patients with abnormal gastrointestinal motility.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Blood sample collection
Study Locations (1)
Maryland
- Johns Hopkins Bayview Medical Center - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2021-04-22 |
| Est. Completion | 2026-12-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04872439
The ClinicalTrials.gov registry entry for NCT04872439 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Autoimmune Gastrointestinal Dysmotility appearing as the primary indexed condition, and to 1 intervention - of which Blood sample collection is the first listed.
NCT04872439 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT04872439 about?
NCT04872439 is a clinical study titled "Novel Antineuronal Antibodies in Gastrointestinal Motility Disorders". Gastrointestinal motility disorders represent a heterogeneous group of neuromuscular diseases of the enteric nervous systems. While autoimmune neuromuscular diseases of the central nervous system (CNS) are well described, the role of autoimmunity in enteric nervous system (ENS) has been less studied...
What is the current status of trial NCT04872439?
This trial is currently active not recruiting. The enrollment target is 300 participants. The study started on 2021-04-22. Estimated completion is 2026-12-31.
What conditions does trial NCT04872439 study?
This clinical trial studies the following conditions: Autoimmune Gastrointestinal Dysmotility.
What interventions are being tested in trial NCT04872439?
The interventions under investigation include: Blood sample collection (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04872439?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04872439 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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