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NCT04860141 · ClinicalTrials.gov registry record · Phase 4
Efficacy of Preoperative Administration of Gabapentin in 3rd Molar Dental Extraction.
A Phase 4 study of Pain, Postoperative and Dental Pain and Sensation Disorder, sponsored by Loma Linda University.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 98
- Enrollment target
- 1
- Study location
NCT04860141: Recruiting Phase 4 study of Pain, Postoperative and Dental Pain and Sensation Disorder, sponsored by Loma Linda University.
NCT04860141 is a Phase 4 study of Pain, Postoperative and Dental Pain and Sensation Disorder that is actively recruiting participants, run by Loma Linda University. The registered enrollment target is 98 participants, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (64% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04860141, a Phase 4 study of Pain, Postoperative and Dental Pain and Sensation Disorder, is actively recruiting participants, sponsored by Loma Linda University.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 98 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is a double-blind, randomized, prospective, placebo-controlled single-center clinical research study in which 600 mg of gabapentin or placebo will be administered 2 hours preoperatively to 49 patients each undergoing wisdom teeth extraction. We will measure intraoperative opioid use, severity of pain, the number of analgesics taken, and side effect profiles (e.g. nausea/vomiting, dizziness) at the following intervals, 4 hour, 8 hour, 12 hour, 24, and 72 hour post-procedure.
Primary Outcome
assess the number of opioid pills (norco 5/325mg) taken postoperatively. #of pills that a patient takes.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Gabapentin 600mg
Study Locations (1)
California
- Loma Linda University Health - Loma Linda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 98 participants |
| Start Date | 2021-06-16 |
| Est. Completion | 2026-12 |
| Phase | Phase 4 |
What NCT04860141 shows while recruiting
NCT04860141 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 98 participants, a relatively small participant target, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (64% lower).
The record links to 2 conditions, with Pain, Postoperative appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT04860141 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04860141 about?
NCT04860141 is a clinical study titled "Efficacy of Preoperative Administration of Gabapentin in 3rd Molar Dental Extraction.". This study is a double-blind, randomized, prospective, placebo-controlled single-center clinical research study in which 600 mg of gabapentin or placebo will be administered 2 hours preoperatively to 49 patients each undergoing wisdom teeth extraction. We will measure intraoperative opioid use, seve...
What is the current status of trial NCT04860141?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 98 participants. The study started on 2021-06-16. Estimated completion is 2026-12.
What conditions does trial NCT04860141 study?
This clinical trial studies the following conditions: Pain, Postoperative, Dental Pain and Sensation Disorder.
What interventions are being tested in trial NCT04860141?
The interventions under investigation include: Placebo (DRUG), Gabapentin 600mg (DRUG).
Who is sponsoring clinical trial NCT04860141?
This trial is sponsored by Loma Linda University, which has 237 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04860141 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain, Postoperative
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04860141's enrollment target sits among peer trials
98 48th of 113 higher than 66 of 113 other Pain, Postoperative trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain, Postoperative trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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