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NCT04857996 · ClinicalTrials.gov registry record · Phase 2

Safety, Tolerability and Evidence of Activity Study of UBX1325 in Patients With Diabetic Macular Edema (BEHOLD)

A Phase 2 study, sponsored by Unity Biotechnology.

Completed
Registry status
Phase 2
Development phase
65
Enrollment target

NCT04857996 is a Phase 2 study that has completed, run by Unity Biotechnology. The registered enrollment target is 65 participants.

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The verdict

NCT04857996, a Phase 2 study, has completed, sponsored by Unity Biotechnology.

COMPLETED
Registry status
Phase 2
Development phase
65 participants
Enrollment target

Study Summary

This study is intended to assess the exposure, safety, biological activity, and durability of UBX1325, a phosphate pro-drug, and its active parent molecule (UBX0601) following a single intravitreal (IVT) injection of UBX1325 in patients with diabetic macular edema (DME).

Interventions

  • OTHER Sham
  • DRUG UBX1325

Trial Details

FieldValue
Enrollment Target 65 participants
Start Date 2021-06-25
Est. Completion 2023-04-06
Phase Phase 2

Sponsor

Unity Biotechnology

9 total trials

What the Registry Record Tells You About NCT04857996

The ClinicalTrials.gov registry entry for NCT04857996 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 65 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Unity Biotechnology, which has 9 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Sham is the first listed.

NCT04857996 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04857996 about?

NCT04857996 is a clinical study titled "Safety, Tolerability and Evidence of Activity Study of UBX1325 in Patients With Diabetic Macular Edema (BEHOLD)". This study is intended to assess the exposure, safety, biological activity, and durability of UBX1325, a phosphate pro-drug, and its active parent molecule (UBX0601) following a single intravitreal (IVT) injection of UBX1325 in patients with diabetic macular edema (DME).

What is the current status of trial NCT04857996?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 65 participants. The study started on 2021-06-25. Estimated completion is 2023-04-06.

What interventions are being tested in trial NCT04857996?

The interventions under investigation include: Sham (OTHER), UBX1325 (DRUG).

Who is sponsoring clinical trial NCT04857996?

This trial is sponsored by Unity Biotechnology, which has 9 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.