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NCT04847921 · ClinicalTrials.gov registry record · Phase 2

Substance Use Disorder (SUD)-Associated Infections' Treatment With Dalbavancin ENabling OUtpatient Transition

A Phase 2 study, sponsored by University of Colorado, Denver.

Terminated
Registry status
Phase 2
Development phase
11
Enrollment target

NCT04847921: Clinical Trial Phase 2 study, sponsored by University of Colorado, Denver.

NCT04847921 is a Phase 2 study that was terminated before completion, run by University of Colorado, Denver. The registered enrollment target is 11 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04847921, a Phase 2 study, was terminated before completion, sponsored by University of Colorado, Denver.

TERMINATED
Registry status
Phase 2
Development phase
11 participants
Enrollment target

Study Summary

The Investigators aim to study the outcomes of serious infections due to vancomycin susceptible infections in gram-positive organisms susceptible to vancomycin in people who use drugs (PWUD). The Investigators hypothesize, that a simplified 2-dose dalbavancin regimen, will improve compliance with antimicrobial therapy and that it may facilitate engagement in the treatment of the underlying substance use disorder, and particularly injection drug use - often the true etiology behind these severe infections.

Primary Outcome

improvement in the principal infectious diagnosis by universally accepted clinically observed clinical features (i.e. deffervescence; improved pain, swelling, purulence)

Interventions

  • DRUG Dalbavancin

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2021-04-30
Est. Completion 2023-10-05
Phase Phase 2
University of Colorado, Denver

1,283 total trials

Why NCT04847921 stopped before completion

NCT04847921 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 1 intervention - of which Dalbavancin is the first listed.

NCT04847921 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04847921 about?

NCT04847921 is a clinical study titled "Substance Use Disorder (SUD)-Associated Infections' Treatment With Dalbavancin ENabling OUtpatient Transition". The Investigators aim to study the outcomes of serious infections due to vancomycin susceptible infections in gram-positive organisms susceptible to vancomycin in people who use drugs (PWUD). The Investigators hypothesize, that a simplified 2-dose dalbavancin regimen, will improve compliance with an...

What is the current status of trial NCT04847921?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 11 participants. The study started on 2021-04-30. Estimated completion is 2023-10-05.

What interventions are being tested in trial NCT04847921?

The interventions under investigation include: Dalbavancin (DRUG).

Who is sponsoring clinical trial NCT04847921?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04847921's enrollment target sits among peer trials

11 1967th of 2000 higher than 33 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04847921, the US trial registry maintained by the National Library of Medicine. NCT04847921 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.