Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04834414 · ClinicalTrials.gov registry record · Phase 3
CHIlled Platelet Study "CHIPS"
A Phase 3 study of Acute Blood Loss, sponsored by Philip Spinella.
- Completed
- Registry status
- Phase 3
- Development phase
- 1,000
- Enrollment target
- 20
- Study locations
NCT04834414: Completed Phase 3 study of Acute Blood Loss, sponsored by Philip Spinella.
NCT04834414 is a Phase 3 study of Acute Blood Loss that has completed, run by Philip Spinella. The registered enrollment target is 1,000 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (30% higher). The trial reports 20 study locations across 15 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04834414, a Phase 3 study of Acute Blood Loss, has completed, sponsored by Philip Spinella.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 1,000 participants
- Enrollment target
- 20
- Study locations
Study Summary
A phase 3 randomized partial blind storage duration ranging study in patients undergoing complex cardiac surgery that will compare the transfusion of cold stored platelets to standard room temperature stored platelets. The primary objective is to establish that cold stored platelets have a non-inferiority (or superiority) to room temperature platelets.
Primary Outcome
Assessed by a bleeding score, a modified Peri-Operative bleeding score: the score ranges from 1-5. A lower score signifies a better outcome.
Conditions Studied
Interventions
- BIOLOGICAL Cold Stored Platelets
- BIOLOGICAL Room Temperature Platelets
Study Locations (20)
Arizona
- Mayo Clinic Arizona - Phoenix
- Banner University Medical Center - Tucson
Illinois
- Northwestern Memorial Hospital - Chicago
- Loyola Universtiy Medical Center - Maywood
Minnesota
- University of Minnesota - Minneapolis
- Mayo Clinic - Rochester
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
- University of Pittsburgh Medical Center - Pittsburgh
Texas
- University of Texas Children's Medical Center - Dallas
- University of Texas Medical Center Clements - Dallas
California
- Ronald Reagan UCLA Medical Center - Los Angeles
Florida
- University of Florida - Gainesville
Kansas
- University of Kansas Medical Center - Kansas City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2021-10-21 |
| Est. Completion | 2025-04-21 |
| Phase | Phase 3 |
What the finished NCT04834414 record still lists
NCT04834414 is an interventional study that assigns participants to a tested intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (30% higher).
The record links to 1 condition, with Acute Blood Loss appearing as the primary indexed condition, and to 2 interventions - of which Cold Stored Platelets is the first listed.
NCT04834414 names 20 study sites across 15 states, led by Arizona, Illinois, Minnesota.
Frequently Asked Questions
What is clinical trial NCT04834414 about?
NCT04834414 is a clinical study titled "CHIlled Platelet Study "CHIPS"". A phase 3 randomized partial blind storage duration ranging study in patients undergoing complex cardiac surgery that will compare the transfusion of cold stored platelets to standard room temperature stored platelets. The primary objective is to establish that cold stored platelets have a non-infer...
What is the current status of trial NCT04834414?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,000 participants. The study started on 2021-10-21. Estimated completion is 2025-04-21.
What conditions does trial NCT04834414 study?
This clinical trial studies the following conditions: Acute Blood Loss.
What interventions are being tested in trial NCT04834414?
The interventions under investigation include: Cold Stored Platelets (BIOLOGICAL), Room Temperature Platelets (BIOLOGICAL).
Who is sponsoring clinical trial NCT04834414?
This trial is sponsored by Philip Spinella, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04834414 being conducted?
This trial has 20 study locations across Arizona, California, Florida, Illinois, Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04834414's enrollment target sits among peer trials
1,000 296th of 2000 higher than 1,689 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00018044 · 1,000 participants
Study of Mycobacterial Infections
- NCT01036581 · 1,000 participants · NA
Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging
- NCT01192048 · 1,000 participants
Genetics of Congenital Heart Disease
- NCT01553214 · 1,000 participants · Phase 4
Improving White Blood Cell Collection From Healthy Donors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI