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NCT04826133 · ClinicalTrials.gov registry record · Early Phase 1
Vitamin D and Cocaine Administration
A Early Phase 1 study, sponsored by Yale University.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 4
- Enrollment target
NCT04826133: Clinical Trial Early Phase 1 study, sponsored by Yale University.
NCT04826133 is a Early Phase 1 study that was terminated before completion, run by Yale University. The registered enrollment target is 4 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04826133, a Early Phase 1 study, was terminated before completion, sponsored by Yale University.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 4 participants
- Enrollment target
Study Summary
This study is designed to explore the effects of acute pre-treatment with 1,25-dihydroxyvitamin D3 (calcitriol), as compared to placebo on the behavioral (e.g., attempts to self-administer and ultimate number of infusions/boluses of cocaine self-administered), neurocognitive (e.g., performance on computerized tests of reward related learning such as the probabilistic selection task or PST and probabilistic reward task or PRT), and subjective effects (e.g, computerized visual analog scale \[VAS\] ratings of euphoria/, craving, etc.) of cocaine in experienced, non-treatment seeking users of the drug.
Primary Outcome
Number of attempts to self administer cocaine will be analyzed.
Interventions
- OTHER Placebo
- DRUG Calcitriol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2019-03-27 |
| Est. Completion | 2020-01-17 |
| Phase | Early Phase 1 |
Why NCT04826133 stopped before completion
NCT04826133 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04826133 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04826133 about?
NCT04826133 is a clinical study titled "Vitamin D and Cocaine Administration". This study is designed to explore the effects of acute pre-treatment with 1,25-dihydroxyvitamin D3 (calcitriol), as compared to placebo on the behavioral (e.g., attempts to self-administer and ultimate number of infusions/boluses of cocaine self-administered), neurocognitive (e.g., performance on co...
What is the current status of trial NCT04826133?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 4 participants. The study started on 2019-03-27. Estimated completion is 2020-01-17.
What interventions are being tested in trial NCT04826133?
The interventions under investigation include: Placebo (OTHER), Calcitriol (DRUG).
Who is sponsoring clinical trial NCT04826133?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04826133's enrollment target sits among peer trials
4 1921st of 2000 higher than 53 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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