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NCT04823273 · ClinicalTrials.gov registry record · NA

Blood Transfusion Reduction - QI Project

A NA study, sponsored by University of Colorado, Denver.

Completed
Registry status
NA
Development phase
1,640
Enrollment target

NCT04823273: Completed NA study, sponsored by University of Colorado, Denver.

NCT04823273 is a NA study that has completed, run by University of Colorado, Denver. The registered enrollment target is 1,640 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (17% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04823273, a NA study, has completed, sponsored by University of Colorado, Denver.

COMPLETED
Registry status
NA
Development phase
1,640 participants
Enrollment target

Study Summary

Blood Banks of large medical centers have large annual budgets, typically millions of dollars. Blood product wastage results in not only in a loss of the product's cost, but also of the fees involved in transporting, handling, and administering these products. Optimal utilization of blood products requires a balance between maximizing patient clinical outcomes while avoiding unnecessary costs and risks associated with transfusions. This project will specifically focus on packed red blood cell transfusions (pRBCs). There are clear guidelines for transfusing pRBCs however these guidelines are not always followed. pRBC transfusions outside of recommended guidelines is associated with increased risk of harm to patients. Our aim is to improve adherence to guideline indicated pRBC transfusions for patient in the UCHealth system thereby decreasing inappropriate (non-guideline indicated) pRBC transfusions. We will conduct a QI project seeking to improve pRBC transfusion guideline adherence. This project will involve data review to establish baseline rates, multimodal interventions to improve adherence to pRBC transfusion guidelines including provider education, modifications to the electronic ordering interface, and changing blood back policies at participating institutions.

Primary Outcome

Number of patients who received blood transfusions during the study by arm.

Interventions

  • BEHAVIORAL General improvement
  • BEHAVIORAL In-line help text
  • BEHAVIORAL Interruptive alert

Trial Details

FieldValue
Enrollment Target 1,640 participants
Start Date 2021-04-06
Est. Completion 2022-10-15
Phase NA
University of Colorado, Denver

1,283 total trials

What the finished NCT04823273 record still lists

NCT04823273 is an interventional study that assigns participants to a tested intervention. Its 1,640 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (17% higher).

The record links to 0 conditions, and to 3 interventions - of which General improvement is the first listed.

NCT04823273 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04823273 about?

NCT04823273 is a clinical study titled "Blood Transfusion Reduction - QI Project". Blood Banks of large medical centers have large annual budgets, typically millions of dollars. Blood product wastage results in not only in a loss of the product's cost, but also of the fees involved in transporting, handling, and administering these products. Optimal utilization of blood products r...

What is the current status of trial NCT04823273?

This trial is currently completed. It is a NA study. The enrollment target is 1,640 participants. The study started on 2021-04-06. Estimated completion is 2022-10-15.

What interventions are being tested in trial NCT04823273?

The interventions under investigation include: General improvement (BEHAVIORAL), In-line help text (BEHAVIORAL), Interruptive alert (BEHAVIORAL).

Who is sponsoring clinical trial NCT04823273?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04823273's enrollment target sits among peer trials

1,640 63rd of 2000 higher than 1,938 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04823273, the US trial registry maintained by the National Library of Medicine. NCT04823273 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.