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NCT04818060 · ClinicalTrials.gov registry record

Preparing for Prevention of Huntington's Disease (PREVENT-HD)

A clinical trial of Huntington Disease, sponsored by University of Wisconsin, Madison.

Completed
Registry status
258
Enrollment target
1
Study location

NCT04818060 is a study of Huntington Disease that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 258 participants, below the 628-participant average among 35 other Huntington Disease trials with a reported enrollment target (59% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04818060, a study of Huntington Disease, has completed, sponsored by University of Wisconsin, Madison.

COMPLETED
Registry status
258 participants
Enrollment target
1
Study location

Study Summary

This is a prospective investigation which aims to address key challenges to the design of clinical trials to prevent the onset of Huntington's disease (HD). The project will provide necessary psychometric data for clinical outcome assessments (COAs) and biomarkers (BMs) in the cerebral spinal fluid (CSF) to address questions of central importance to the success of these measures for premanifest clinical trials. Of the 258 participants: 52 will be low risk of motor diagnosis, 102 high risk of motor diagnosis, 52 with diagnosed HD (stages I or II), and 52 healthy controls. Participants can expect to be in the study for up to 2 years.

Conditions Studied

Interventions

  • DIAGNOSTIC_TEST MRI Scan
  • OTHER Clinical Assessments
  • DIAGNOSTIC_TEST Lumber Puncture (LP)

Study Locations (1)

Wisconsin

  • University of Wisconsin - Madison

Trial Details

FieldValue
Enrollment Target 258 participants
Start Date 2021-09-13
Est. Completion 2025-01-31

Sponsor

University of Wisconsin, Madison

1,039 total trials

What the Registry Record Tells You About NCT04818060

The ClinicalTrials.gov registry entry for NCT04818060 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 258 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 628-participant average among 35 other Huntington Disease trials with a reported enrollment target (59% lower). The listed sponsor is University of Wisconsin, Madison, which has 1,039 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Huntington Disease appearing as the primary indexed condition, and to 3 interventions - of which MRI Scan is the first listed.

NCT04818060 reports 1 study location spanning 1 distinct geographic area - top geographies include Wisconsin.

Frequently Asked Questions

What is clinical trial NCT04818060 about?

NCT04818060 is a clinical study titled "Preparing for Prevention of Huntington's Disease (PREVENT-HD)". This is a prospective investigation which aims to address key challenges to the design of clinical trials to prevent the onset of Huntington's disease (HD). The project will provide necessary psychometric data for clinical outcome assessments (COAs) and biomarkers (BMs) in the cerebral spinal fluid ...

What is the current status of trial NCT04818060?

This trial is currently completed. The enrollment target is 258 participants. The study started on 2021-09-13. Estimated completion is 2025-01-31.

What conditions does trial NCT04818060 study?

This clinical trial studies the following conditions: Huntington Disease.

What interventions are being tested in trial NCT04818060?

The interventions under investigation include: MRI Scan (DIAGNOSTIC_TEST), Clinical Assessments (OTHER), Lumber Puncture (LP) (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT04818060?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04818060 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.