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NCT04816149 · ClinicalTrials.gov registry record · NA

Treatment for Relationships and Safety Together

A NA study of Suicide and Interpersonal Relations, sponsored by VA Office of Research and Development.

Active
Registry status
NA
Development phase
104
Enrollment target
1
Study location

NCT04816149: Active NA study of Suicide and Interpersonal Relations, sponsored by VA Office of Research and Development.

NCT04816149 is a NA study of Suicide and Interpersonal Relations that is active but no longer recruiting, run by VA Office of Research and Development. The registered enrollment target is 104 participants, below the 6,989-participant average among 92 other Suicide trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04816149, a NA study of Suicide and Interpersonal Relations, is active but no longer recruiting, sponsored by VA Office of Research and Development.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
104 participants
Enrollment target
1
Study location

Study Summary

Suicide prevention is the top clinical priority for VA/DoD. Suicide is one of the leading causes of death in the United States and worldwide with suicide rates among U.S. military Veterans doubling (27.7 per 100,000) the rate of civilian levels. Despite a rise in prevention efforts, rates have continued to increase. Theories of suicide and rehabilitation psychology stress the importance of the person-environment interaction in contributing to one's disability experience. Several studies have found that the most frequent situation precipitating suicide was a problem with a romantic partner. In contrast, people with higher relationship satisfaction are less likely to have suicidal thoughts. Prevention of suicide in high risk Veterans is of vital importance and the quality of one's intimate relationship is an understudied intervention target for suicide prevention. Despite the fact that VA/DoD recommend and Veterans desire treatments that involve family members, currently no couple-based suicide-specific interventions exist. The goals of this CDA-II proposal are to refine and pilot a novel suicide-specific couple-based intervention: Treatment for Relationships and Safety Together (TR\&ST). TR\&ST adapts an evidence-based intervention for suicide, Brief Cognitive Behavioral Therapy (BCBT) for Suicide, to be dyadically focused and integrates Cognitive Behavioral Couple Therapy (CBCT) skills. The proposed 5-year study consists of two phases. Phase 1: treatment refinement with 12 couples (N=24) and Phase 2: pilot Randomized Controlled Trial (RCT) of TR\&ST compared to VA Standard Suicide Intervention, which will involve suicide risk assessment, VA safety planning, Suicide Prevention Coordinator (SPC) follow-up, and referral to outpatient mental health with 60 couples (N=120). The intervention period is 11-weeks and the entire study period is approximately 7 months. Couples in both phases will be quantitatively assessed at baseline, mid-treatment, post-treatment, and 3-mont

Primary Outcome

The Beck Scale for Suicidal Ideation has a minimum possible score of 0, and maximum possible score of 38, wherein higher scores reflect more severe suicidal ideation.

Conditions Studied

Suicide Interpersonal Relations

Interventions

  • BEHAVIORAL VA Standard Suicide Intervention
  • BEHAVIORAL Treatment for Relationships and Safety Together (TR&ST)

Study Locations (1)

California

  • VA San Diego Healthcare System, San Diego, CA - San Diego

Trial Details

FieldValue
Enrollment Target 104 participants
Start Date 2021-04-15
Est. Completion 2026-03-31
Phase NA
VA Office of Research and Development

1,668 total trials

What the registry record for NCT04816149 still lists

NCT04816149 is an interventional study that assigns participants to a tested intervention. The registered 104 participants enrollment target is mid-sized for trials with a published cap, below the 6,989-participant average among 92 other Suicide trials with a reported enrollment target (99% lower).

The record links to 2 conditions, with Suicide appearing as the primary indexed condition, and to 2 interventions - of which VA Standard Suicide Intervention is the first listed.

NCT04816149 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT04816149 about?

NCT04816149 is a clinical study titled "Treatment for Relationships and Safety Together". Suicide prevention is the top clinical priority for VA/DoD. Suicide is one of the leading causes of death in the United States and worldwide with suicide rates among U.S. military Veterans doubling (27.7 per 100,000) the rate of civilian levels. Despite a rise in prevention efforts, rates have conti...

What is the current status of trial NCT04816149?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 104 participants. The study started on 2021-04-15. Estimated completion is 2026-03-31.

What conditions does trial NCT04816149 study?

This clinical trial studies the following conditions: Suicide, Interpersonal Relations.

What interventions are being tested in trial NCT04816149?

The interventions under investigation include: VA Standard Suicide Intervention (BEHAVIORAL), Treatment for Relationships and Safety Together (TR&ST) (BEHAVIORAL).

Who is sponsoring clinical trial NCT04816149?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04816149 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Suicide

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04816149's enrollment target sits among peer trials

104 46th of 92 higher than 47 of 92 other Suicide trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Suicide trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT04816149, the US trial registry maintained by the National Library of Medicine. NCT04816149 (mid enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.