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NCT04814433 · ClinicalTrials.gov registry record · Phase 4
Evaluating Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation
A Phase 4 study, sponsored by NYU Langone Health.
- Terminated
- Registry status
- Phase 4
- Development phase
- 46
- Enrollment target
NCT04814433: Clinical Trial Phase 4 study, sponsored by NYU Langone Health.
NCT04814433 is a Phase 4 study that was terminated before completion, run by NYU Langone Health. The registered enrollment target is 46 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04814433, a Phase 4 study, was terminated before completion, sponsored by NYU Langone Health.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 46 participants
- Enrollment target
Study Summary
This study is a prospective randomized trial examining the effect of topically combined antifibrinolytics (Tranexamic acid) with local anesthetics in all electively created surgical wound beds in hand surgery to provide long term pain relief and decrease the use of postoperative narcotics.
Primary Outcome
Measured by self-reported level of pain recorded in a daily pain diary made by the researchers from the day of the surgery until post-operative day 14. The levels of pain are scored in the following manner: 1-2 no pain, 3-4 mild pain, 5-6 moderate pain, 7-8 severe pain, 9-10 worst pain imaginable.
Interventions
- DRUG Tranexamic acid
- DRUG Aminocaproic acid
- DRUG Recombinant Human Thrombin
- DRUG Lidocaine Hydrochloride with Epinephrine
- DRUG Bupivacaine Hydrochloride with Epinephrine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2021-03-24 |
| Est. Completion | 2023-07-10 |
| Phase | Phase 4 |
Why NCT04814433 stopped before completion
NCT04814433 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (91% lower).
The record links to 0 conditions, and to 5 interventions - of which Tranexamic acid is the first listed.
NCT04814433 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04814433 about?
NCT04814433 is a clinical study titled "Evaluating Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation". This study is a prospective randomized trial examining the effect of topically combined antifibrinolytics (Tranexamic acid) with local anesthetics in all electively created surgical wound beds in hand surgery to provide long term pain relief and decrease the use of postoperative narcotics.
What is the current status of trial NCT04814433?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 46 participants. The study started on 2021-03-24. Estimated completion is 2023-07-10.
What interventions are being tested in trial NCT04814433?
The interventions under investigation include: Tranexamic acid (DRUG), Aminocaproic acid (DRUG), Recombinant Human Thrombin (DRUG), Lidocaine Hydrochloride with Epinephrine (DRUG), Bupivacaine Hydrochloride with Epinephrine (DRUG).
Who is sponsoring clinical trial NCT04814433?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04814433's enrollment target sits among peer trials
46 1348th of 2000 higher than 647 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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