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NCT04809818 · ClinicalTrials.gov registry record · Phase 1

A Study to Evaluate Safety and PK of Multiple Doses of LT3001 Drug Product and Drug-drug Interaction in Healthy Subjects

A Phase 1 study, sponsored by Lumosa Therapeutics Co..

Completed
Registry status
Phase 1
Development phase
65
Enrollment target

NCT04809818: Completed Phase 1 study, sponsored by Lumosa Therapeutics Co..

NCT04809818 is a Phase 1 study that has completed, run by Lumosa Therapeutics Co.. The registered enrollment target is 65 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04809818, a Phase 1 study, has completed, sponsored by Lumosa Therapeutics Co..

COMPLETED
Registry status
Phase 1
Development phase
65 participants
Enrollment target

Study Summary

This Phase 1 study is planned to establish the clinical safety and pharmacokinetics profile of multiple dose of LT3001 drug product and to investigate drug interactions of LT3001 with potential concomitant medications in healthy subjects.

Primary Outcome

To evaluate the safety and tolerability of LT3001 administered alone or in combination with aspirin, clopidogrel, apixaban, or dabigatran, as determined by the number and severity of adverse events collected from baseline through Day 4 post-baseline in Part A, and from baseline through Day 16 post-baseline in Part B.

Interventions

  • DRUG Placebo
  • DRUG Aspirin
  • DRUG Apixaban
  • DRUG Clopidogrel
  • DRUG LT3001 drug product

Trial Details

FieldValue
Enrollment Target 65 participants
Start Date 2021-03-21
Est. Completion 2021-08-05
Phase Phase 1
Lumosa Therapeutics Co.

5 total trials

What the finished NCT04809818 record still lists

NCT04809818 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.

The record links to 0 conditions, and to 5 interventions - of which Placebo is the first listed.

NCT04809818 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04809818 about?

NCT04809818 is a clinical study titled "A Study to Evaluate Safety and PK of Multiple Doses of LT3001 Drug Product and Drug-drug Interaction in Healthy Subjects". This Phase 1 study is planned to establish the clinical safety and pharmacokinetics profile of multiple dose of LT3001 drug product and to investigate drug interactions of LT3001 with potential concomitant medications in healthy subjects.

What is the current status of trial NCT04809818?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 65 participants. The study started on 2021-03-21. Estimated completion is 2021-08-05.

What interventions are being tested in trial NCT04809818?

The interventions under investigation include: Placebo (DRUG), Aspirin (DRUG), Apixaban (DRUG), Clopidogrel (DRUG), LT3001 drug product (DRUG).

Who is sponsoring clinical trial NCT04809818?

This trial is sponsored by Lumosa Therapeutics Co., which has 5 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04809818's enrollment target sits among peer trials

65 798th of 2000 higher than 1,193 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04809818, the US trial registry maintained by the National Library of Medicine. NCT04809818 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.