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NCT04804007 · ClinicalTrials.gov registry record · Phase 2
Maintenance Oral Etoposide or Observation Following High-dose Chemo for GCT
A Phase 2 study of Germ Cell Tumor and Ovarian Germ Cell Tumor, sponsored by Nabil Adra.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 64
- Enrollment target
- 1
- Study location
NCT04804007: Recruiting Phase 2 study of Germ Cell Tumor and Ovarian Germ Cell Tumor, sponsored by Nabil Adra.
NCT04804007 is a Phase 2 study of Germ Cell Tumor and Ovarian Germ Cell Tumor that is actively recruiting participants, run by Nabil Adra. The registered enrollment target is 64 participants, below the 344-participant average among 19 other Germ Cell Tumor trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04804007, a Phase 2 study of Germ Cell Tumor and Ovarian Germ Cell Tumor, is actively recruiting participants, sponsored by Nabil Adra.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 64 participants
- Enrollment target
- 1
- Study location
Study Summary
This is an open label randomized phase II trial of maintenance oral etoposide vs. observation in patinets with relapsed GCT treated with high-dose chemotherapy (HDCT) and peripheral-blood stem-cell transplant (PBSCT).
Primary Outcome
Investigator determination of tumor progression (clinical, radiographic, tumor markers including AFP and hCG)
Conditions Studied
Interventions
- DRUG Etoposide
Study Locations (1)
Indiana
- Indiana University Melvin & Bren Simon Cancer Center - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 64 participants |
| Start Date | 2021-03-03 |
| Est. Completion | 2028-12 |
| Phase | Phase 2 |
What NCT04804007 shows while recruiting
NCT04804007 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 64 participants, a relatively small participant target, below the 344-participant average among 19 other Germ Cell Tumor trials with a reported enrollment target (81% lower).
The record links to 3 conditions, with Germ Cell Tumor appearing as the primary indexed condition, and to 1 intervention - of which Etoposide is the first listed.
NCT04804007 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT04804007 about?
NCT04804007 is a clinical study titled "Maintenance Oral Etoposide or Observation Following High-dose Chemo for GCT". This is an open label randomized phase II trial of maintenance oral etoposide vs. observation in patinets with relapsed GCT treated with high-dose chemotherapy (HDCT) and peripheral-blood stem-cell transplant (PBSCT).
What is the current status of trial NCT04804007?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 64 participants. The study started on 2021-03-03. Estimated completion is 2028-12.
What conditions does trial NCT04804007 study?
This clinical trial studies the following conditions: Germ Cell Tumor, Ovarian Germ Cell Tumor, Non-seminomatous Germ Cell Tumor.
What interventions are being tested in trial NCT04804007?
The interventions under investigation include: Etoposide (DRUG).
Who is sponsoring clinical trial NCT04804007?
This trial is sponsored by Nabil Adra, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04804007 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Germ Cell Tumor
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04804007's enrollment target sits among peer trials
64 10th of 19 higher than 10 of 19 other Germ Cell Tumor trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Germ Cell Tumor trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
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Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
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