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NCT04783506 · ClinicalTrials.gov registry record
Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents
A clinical trial of Suicide and Depression, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- 225
- Enrollment target
- 1
- Study location
NCT04783506: Completed study of Suicide and Depression, sponsored by University of Texas Southwestern Medical Center.
NCT04783506 is a study of Suicide and Depression that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 225 participants, below the 324-participant average among 3 other Suicide and Depression trials with a reported enrollment target (31% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04783506, a study of Suicide and Depression, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- 225 participants
- Enrollment target
- 1
- Study location
Study Summary
Despite increasing suicide rates in adolescents, there remains a paucity of approaches to use to prevent re-attempts. Any hope for breaking the code to prevent youth suicide lies in understanding biological factors that play a role. Evidence suggests that inflammation and immune system dysfunction may be linked to suicide. The investigators will develop immune profiles for adolescents with suicidal behavior and those at risk in order to develop tools that can be implemented for prevention efforts. This study involves blood draws, answering questions, and completing questionnaires - no treatment or intervention is provided as part of this study. Participants will be screened to see if they qualify for this study using questionnaires. Participants will be teens (ages 12-18 years) with recent suicidal behavior, teens at-risk for developing depression, and healthy control teens. Participants complete all study-related tasks four times over a period of 12 months. Electronic surveys will be sent to participants to complete monthly. Both the adolescent and if applicable, their parent (or legally authorized representatives, LARs), will answer questions regarding depression, anxiety, and suicidal thoughts/behaviors.
Primary Outcome
This will be accomplished by characterization of cells that mediate immune response. Numbers of these cells in blood and how they respond to immune stimulation will be compared between groups of adolescents with varying levels of suicidal behavior.
Conditions Studied
Interventions
- OTHER Observational Study
Study Locations (1)
Texas
- University of Texas Southwestern Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 225 participants |
| Start Date | 2021-04-28 |
| Est. Completion | 2025-08-31 |
What the finished NCT04783506 record still lists
NCT04783506 is an observational study that tracks outcomes without assigning an intervention. The registered 225 participants enrollment target is mid-sized for trials with a published cap, below the 324-participant average among 3 other Suicide and Depression trials with a reported enrollment target (31% lower).
The record links to 1 condition, with Suicide and Depression appearing as the primary indexed condition, and to 1 intervention - of which Observational Study is the first listed.
NCT04783506 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT04783506 about?
NCT04783506 is a clinical study titled "Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents". Despite increasing suicide rates in adolescents, there remains a paucity of approaches to use to prevent re-attempts. Any hope for breaking the code to prevent youth suicide lies in understanding biological factors that play a role. Evidence suggests that inflammation and immune system dysfunction m...
What is the current status of trial NCT04783506?
This trial is currently completed. The enrollment target is 225 participants. The study started on 2021-04-28. Estimated completion is 2025-08-31.
What conditions does trial NCT04783506 study?
This clinical trial studies the following conditions: Suicide and Depression.
What interventions are being tested in trial NCT04783506?
The interventions under investigation include: Observational Study (OTHER).
Who is sponsoring clinical trial NCT04783506?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04783506 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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