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NCT04781972 · ClinicalTrials.gov registry record · Phase 4
Multimodal Brain Imaging of the Neural Effects of Methylphenidate in Patients With ADHD
A Phase 4 study of ADHD - Combined Type, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT04781972 is a Phase 4 study of ADHD - Combined Type that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 30 participants. The trial reports 1 study location across 1 state.
The verdict
NCT04781972, a Phase 4 study of ADHD - Combined Type, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators' goal is to develop neuroimaging biomarkers to predict response to treatment with methylphenidate, which then can be used in the development of novel pharmacological treatments for attention-deficit/hyperactivity disorder (ADHD). The overall objective of this study is to measure the changes in task-related neural activity related to symptoms of ADHD (measured by functional MRI) and brain glutamate levels (measured by magnetic resonance spectroscopy, MRS) after treatment with methylphenidate (MPH). This will be a double-blind crossover of methylphenidate and placebo in adults with ADHD. Participants will complete neuropsychological testing along with fMRI and MRS scans after a single dose of each treatment.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Methylphenidate
Study Locations (1)
Maryland
- Johns Hopkins School of Medicine - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2021-07-27 |
| Est. Completion | 2029-04-30 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04781972
The ClinicalTrials.gov registry entry for NCT04781972 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with ADHD - Combined Type appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT04781972 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT04781972 about?
NCT04781972 is a clinical study titled "Multimodal Brain Imaging of the Neural Effects of Methylphenidate in Patients With ADHD". The investigators' goal is to develop neuroimaging biomarkers to predict response to treatment with methylphenidate, which then can be used in the development of novel pharmacological treatments for attention-deficit/hyperactivity disorder (ADHD). The overall objective of this study is to measure th...
What is the current status of trial NCT04781972?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 30 participants. The study started on 2021-07-27. Estimated completion is 2029-04-30.
What conditions does trial NCT04781972 study?
This clinical trial studies the following conditions: ADHD - Combined Type.
What interventions are being tested in trial NCT04781972?
The interventions under investigation include: Placebo (DRUG), Methylphenidate (DRUG).
Who is sponsoring clinical trial NCT04781972?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04781972 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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