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NCT04778644 · ClinicalTrials.gov registry record · Phase 1
Hippocampal Response to Acute Oral Doses of CBD During an fMRI Memory Task
A Phase 1 study of CBD, sponsored by Hartford Hospital.
- Active
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT04778644 is a Phase 1 study of CBD that is active but no longer recruiting, run by Hartford Hospital. The registered enrollment target is 20 participants, below the 65-participant average among 8 other CBD trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04778644, a Phase 1 study of CBD, is active but no longer recruiting, sponsored by Hartford Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
Cannabidiol (CBD) is another cannabis plant derivative for which, like THC, there has been extensive research. Unlike THC however, CBD is non-intoxicating and non-psychedelic. CBD has antipsychotic effects. Logically, if CBD opposes THC effects, it may be a potential antipsychotic treatment. The purpose of this pilot research is to show target engagement of the hippocampus with the study drug (CBD versus placebo) in patients who have been diagnosed with schizophrenia, schizoaffective disorder, or bipolar disorder with psychosis compared to healthy controls.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG CBD
Study Locations (1)
Connecticut
- Hartford Hospital - Hartford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2021-12-15 |
| Est. Completion | 2025-12-15 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04778644
The ClinicalTrials.gov registry entry for NCT04778644 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 65-participant average among 8 other CBD trials with a reported enrollment target (69% lower). The listed sponsor is Hartford Hospital, which has 75 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with CBD appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT04778644 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.
Frequently Asked Questions
What is clinical trial NCT04778644 about?
NCT04778644 is a clinical study titled "Hippocampal Response to Acute Oral Doses of CBD During an fMRI Memory Task". Cannabidiol (CBD) is another cannabis plant derivative for which, like THC, there has been extensive research. Unlike THC however, CBD is non-intoxicating and non-psychedelic. CBD has antipsychotic effects. Logically, if CBD opposes THC effects, it may be a potential antipsychotic treatment. The pur...
What is the current status of trial NCT04778644?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2021-12-15. Estimated completion is 2025-12-15.
What conditions does trial NCT04778644 study?
This clinical trial studies the following conditions: CBD.
What interventions are being tested in trial NCT04778644?
The interventions under investigation include: Placebo (DRUG), CBD (DRUG).
Who is sponsoring clinical trial NCT04778644?
This trial is sponsored by Hartford Hospital, which has 75 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04778644 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.