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NCT04774328 · ClinicalTrials.gov registry record · Phase 1
Preliminary Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia Repair
A Phase 1 study, sponsored by Concentric Analgesics.
- Completed
- Registry status
- Phase 1
- Development phase
- 34
- Enrollment target
NCT04774328: Completed Phase 1 study, sponsored by Concentric Analgesics.
NCT04774328 is a Phase 1 study that has completed, run by Concentric Analgesics. The registered enrollment target is 34 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (43% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04774328, a Phase 1 study, has completed, sponsored by Concentric Analgesics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 34 participants
- Enrollment target
Study Summary
A Three-Part, Phase 1/2, Randomized, Double-blind, Placebo-Controlled, Adaptive Safety, Pharmacokinetics, and Preliminary Efficacy Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia Repair
Primary Outcome
Pain at rest measured by a Numeric Rating Scale (NRS) from time 0 to 96 hours (AUC 0-96). NRS pain scores at rest were collected at 1, 2, 4, 6, 8, 12, 16, 20, 24 and every 4 hours there after post the time of entry into the PACU (while the patient is awake), until discharge from the inpatient until at 96 hour. NRS area under the curve (AUC) is the weighted sum of current pain intensity assessments for a specified time interval. The NRS ranks pain from 0-10; zero being no pain present and 10 bein
Interventions
- DRUG Placebo
- DRUG CA-008 (vocacapsaicin)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2020-09-09 |
| Est. Completion | 2021-06-15 |
| Phase | Phase 1 |
What the finished NCT04774328 record still lists
NCT04774328 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (43% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04774328 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04774328 about?
NCT04774328 is a clinical study titled "Preliminary Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia Repair". A Three-Part, Phase 1/2, Randomized, Double-blind, Placebo-Controlled, Adaptive Safety, Pharmacokinetics, and Preliminary Efficacy Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia Repair
What is the current status of trial NCT04774328?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 34 participants. The study started on 2020-09-09. Estimated completion is 2021-06-15.
What interventions are being tested in trial NCT04774328?
The interventions under investigation include: Placebo (DRUG), CA-008 (vocacapsaicin) (DRUG).
Who is sponsoring clinical trial NCT04774328?
This trial is sponsored by Concentric Analgesics, which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04774328's enrollment target sits among peer trials
34 1273rd of 2000 higher than 721 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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