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NCT04774237 · ClinicalTrials.gov registry record · Phase 2

Safety and Efficacy Study of BRIMOCHOL™, BRIMOCHOL™ F, and Carbachol in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia

A Phase 2 study, sponsored by Visus Therapeutics.

Completed
Registry status
Phase 2
Development phase
18
Enrollment target

NCT04774237: Completed Phase 2 study, sponsored by Visus Therapeutics.

NCT04774237 is a Phase 2 study that has completed, run by Visus Therapeutics. The registered enrollment target is 18 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04774237, a Phase 2 study, has completed, sponsored by Visus Therapeutics.

COMPLETED
Registry status
Phase 2
Development phase
18 participants
Enrollment target

Study Summary

Safety and Efficacy Study of BRIMOCHOL™ vs. BRIMOCHOL™ F vs. Carbachol Monotherapy Topical Ophthalmic Solutions in Subjects with Emmetropic Phakic and Pseudophakic Presbyopia

Primary Outcome

Primary Endpoint measured at Hour 1 post-dose at Study Visit - a Single drop Cohort

Interventions

  • DRUG BRIMOCHOL™
  • DRUG BRIMOCHOL™ F
  • DRUG Carbachol

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2021-03-24
Est. Completion 2021-10-19
Phase Phase 2
Visus Therapeutics

3 total trials

What the finished NCT04774237 record still lists

NCT04774237 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower).

The record links to 0 conditions, and to 3 interventions - of which BRIMOCHOL™ is the first listed.

NCT04774237 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04774237 about?

NCT04774237 is a clinical study titled "Safety and Efficacy Study of BRIMOCHOL™, BRIMOCHOL™ F, and Carbachol in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia". Safety and Efficacy Study of BRIMOCHOL™ vs. BRIMOCHOL™ F vs. Carbachol Monotherapy Topical Ophthalmic Solutions in Subjects with Emmetropic Phakic and Pseudophakic Presbyopia

What is the current status of trial NCT04774237?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 18 participants. The study started on 2021-03-24. Estimated completion is 2021-10-19.

What interventions are being tested in trial NCT04774237?

The interventions under investigation include: BRIMOCHOL™ (DRUG), BRIMOCHOL™ F (DRUG), Carbachol (DRUG).

Who is sponsoring clinical trial NCT04774237?

This trial is sponsored by Visus Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04774237's enrollment target sits among peer trials

18 1898th of 2000 higher than 98 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04774237, the US trial registry maintained by the National Library of Medicine. NCT04774237 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.