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NCT04772196 · ClinicalTrials.gov registry record · Early Phase 1
Temporal Profile of Serum Vitamin D Levels in Foot and Ankle Fusion Surgery
A Early Phase 1 study of Ankle Arthrodesis and MTP Arthrodesis, sponsored by Prisma Health-Midlands.
- Active
- Registry status
- Early Phase 1
- Development phase
- 90
- Enrollment target
- 2
- Study locations
NCT04772196: Active Early Phase 1 study of Ankle Arthrodesis and MTP Arthrodesis, sponsored by Prisma Health-Midlands.
NCT04772196 is a Early Phase 1 study of Ankle Arthrodesis and MTP Arthrodesis that is active but no longer recruiting, run by Prisma Health-Midlands. The registered enrollment target is 90 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (70% higher). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04772196, a Early Phase 1 study of Ankle Arthrodesis and MTP Arthrodesis, is active but no longer recruiting, sponsored by Prisma Health-Midlands.
- ACTIVE NOT RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 90 participants
- Enrollment target
- 2
- Study locations
Study Summary
Vitamin D is important for bone health and recent research has emphasized the importance of adequate vitamin D levels for bone healing, wound healing, and possibly preventing infections post-operatively. This study will assess the effect of vitamin D supplementation on patient outcomes following ankle arthrodesis or first metatarsophalangeal joint arthrodesis.
Primary Outcome
Patients will be followed for 6 months post-operatively to determine overall complication rate in patients receiving Vitamin D3 supplementation vs. standard of care. Complications will include infection, wound healing complications, readmission, re-operation, and clinical or radiographic nonunion.
Conditions Studied
Interventions
- DRUG Vitamin D3
Study Locations (2)
South Carolina
- Medical University of South Carolina - Charleston
- Prisma Health - Columbia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2020-12-21 |
| Est. Completion | 2026-05 |
| Phase | Early Phase 1 |
What the registry record for NCT04772196 still lists
NCT04772196 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (70% higher).
The record links to 2 conditions, with Ankle Arthrodesis appearing as the primary indexed condition, and to 1 intervention - of which Vitamin D3 is the first listed.
NCT04772196 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT04772196 about?
NCT04772196 is a clinical study titled "Temporal Profile of Serum Vitamin D Levels in Foot and Ankle Fusion Surgery". Vitamin D is important for bone health and recent research has emphasized the importance of adequate vitamin D levels for bone healing, wound healing, and possibly preventing infections post-operatively. This study will assess the effect of vitamin D supplementation on patient outcomes following ank...
What is the current status of trial NCT04772196?
This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 90 participants. The study started on 2020-12-21. Estimated completion is 2026-05.
What conditions does trial NCT04772196 study?
This clinical trial studies the following conditions: Ankle Arthrodesis, MTP Arthrodesis.
What interventions are being tested in trial NCT04772196?
The interventions under investigation include: Vitamin D3 (DRUG).
Who is sponsoring clinical trial NCT04772196?
This trial is sponsored by Prisma Health-Midlands, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04772196 being conducted?
This trial has 2 study locations across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Ankle Arthrodesis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04772196's enrollment target sits among peer trials
90 233rd of 2000 higher than 1,753 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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