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NCT04753606 · ClinicalTrials.gov registry record · Phase 2
Randomized Study of Obicetrapib as an Adjunct to Statin Therapy
A Phase 2 study, sponsored by NewAmsterdam Pharma.
- Completed
- Registry status
- Phase 2
- Development phase
- 120
- Enrollment target
NCT04753606: Completed Phase 2 study, sponsored by NewAmsterdam Pharma.
NCT04753606 is a Phase 2 study that has completed, run by NewAmsterdam Pharma. The registered enrollment target is 120 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (10% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04753606, a Phase 2 study, has completed, sponsored by NewAmsterdam Pharma.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 120 participants
- Enrollment target
Study Summary
This study will be a placebo-controlled, double-blind, randomized, phase 2 dose-finding study to evaluate the efficacy, safety, and tolerability of obicetrapib as an adjunct to high-intensity statin therapy.
Primary Outcome
Mean percent change from Day 1 to Day 56 in Low-Density Lipoprotein Cholesterol (LDL-C) for each obicetrapib group compared to the placebo group.LDL-C was calculated using the Friedewald equation unless TG ≥400 mg/dL or LDL-C ≤50 mg/dL; if TG ≥400 mg/dL or LDL-C ≤50 mg/dL, then LDL-C level was measured directly by preparative ultracentrifugation (PUC),
Interventions
- DRUG Obicetrapib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2021-02-18 |
| Est. Completion | 2021-08-30 |
| Phase | Phase 2 |
What the finished NCT04753606 record still lists
NCT04753606 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (10% lower).
The record links to 0 conditions, and to 1 intervention - of which Obicetrapib is the first listed.
NCT04753606 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04753606 about?
NCT04753606 is a clinical study titled "Randomized Study of Obicetrapib as an Adjunct to Statin Therapy". This study will be a placebo-controlled, double-blind, randomized, phase 2 dose-finding study to evaluate the efficacy, safety, and tolerability of obicetrapib as an adjunct to high-intensity statin therapy.
What is the current status of trial NCT04753606?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 120 participants. The study started on 2021-02-18. Estimated completion is 2021-08-30.
What interventions are being tested in trial NCT04753606?
The interventions under investigation include: Obicetrapib (DRUG).
Who is sponsoring clinical trial NCT04753606?
This trial is sponsored by NewAmsterdam Pharma, which has 15 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04753606's enrollment target sits among peer trials
120 569th of 2000 higher than 1,383 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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