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NCT04750655 · ClinicalTrials.gov registry record · Phase 4

Antibiotic Resistance In Eye Surgeries

A Phase 4 study, sponsored by University of California, San Francisco.

Completed
Registry status
Phase 4
Development phase
108
Enrollment target

NCT04750655: Completed Phase 4 study, sponsored by University of California, San Francisco.

NCT04750655 is a Phase 4 study that has completed, run by University of California, San Francisco. The registered enrollment target is 108 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (79% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04750655, a Phase 4 study, has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
Phase 4
Development phase
108 participants
Enrollment target

Study Summary

In this study, the investigators seek to determine the effect of antibiotic use post-surgery on antimicrobial resistance. The investigators will be studying adults (aged 18 or older) who will undergo eye surgery at University of California, San Francisco (UCSF). We seek to gain a better understanding of how antibiotic use during the perioperative period influences local and systemic antibiotic resistance at the individual level.

Primary Outcome

Normalized read counts (reads per million reads or rM) for fluoroquinolone resistance determinants from DNA deep sequencing for the conjunctival swabs at 1 week, which represent the abundance of resistance in the sample.

Interventions

  • DRUG Moxifloxacin (Topical)

Trial Details

FieldValue
Enrollment Target 108 participants
Start Date 2021-03-01
Est. Completion 2023-08-31
Phase Phase 4

What the finished NCT04750655 record still lists

NCT04750655 is an interventional study that assigns participants to a tested intervention. The registered 108 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (79% lower).

The record links to 0 conditions, and to 1 intervention - of which Moxifloxacin (Topical) is the first listed.

NCT04750655 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04750655 about?

NCT04750655 is a clinical study titled "Antibiotic Resistance In Eye Surgeries". In this study, the investigators seek to determine the effect of antibiotic use post-surgery on antimicrobial resistance. The investigators will be studying adults (aged 18 or older) who will undergo eye surgery at University of California, San Francisco (UCSF). We seek to gain a better understandin...

What is the current status of trial NCT04750655?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 108 participants. The study started on 2021-03-01. Estimated completion is 2023-08-31.

What interventions are being tested in trial NCT04750655?

The interventions under investigation include: Moxifloxacin (Topical) (DRUG).

Who is sponsoring clinical trial NCT04750655?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04750655's enrollment target sits among peer trials

108 740th of 2000 higher than 1,256 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04750655, the US trial registry maintained by the National Library of Medicine. NCT04750655 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.