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NCT04745351 · ClinicalTrials.gov registry record · Phase 3

Study to Evaluate the Efficacy and Safety of Remdesivir in Participants With Severely Reduced Kidney Function Who Are Hospitalized for Coronavirus Disease 2019 (COVID-19)

A Phase 3 study, sponsored by Gilead Sciences.

Terminated
Registry status
Phase 3
Development phase
249
Enrollment target

NCT04745351 is a Phase 3 study that was terminated before completion, run by Gilead Sciences. The registered enrollment target is 249 participants.

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The verdict

NCT04745351, a Phase 3 study, was terminated before completion, sponsored by Gilead Sciences.

TERMINATED
Registry status
Phase 3
Development phase
249 participants
Enrollment target

Study Summary

The primary objective of this study is to evaluate whether remdesivir (RDV, GS-5734™) reduces the composite risk of death or invasive mechanical ventilation (IMV) through Day 29 in participants with severely reduced kidney function who are hospitalized for coronavirus disease 2019 (COVID-19).

Interventions

  • DRUG Standard of Care
  • DRUG Remdesivir
  • DRUG RDV Placebo

Trial Details

FieldValue
Enrollment Target 249 participants
Start Date 2021-03-31
Est. Completion 2022-05-24
Phase Phase 3

Sponsor

Gilead Sciences

504 total trials

What the Registry Record Tells You About NCT04745351

The ClinicalTrials.gov registry entry for NCT04745351 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 249 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gilead Sciences, which has 504 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Standard of Care is the first listed.

NCT04745351 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04745351 about?

NCT04745351 is a clinical study titled "Study to Evaluate the Efficacy and Safety of Remdesivir in Participants With Severely Reduced Kidney Function Who Are Hospitalized for Coronavirus Disease 2019 (COVID-19)". The primary objective of this study is to evaluate whether remdesivir (RDV, GS-5734™) reduces the composite risk of death or invasive mechanical ventilation (IMV) through Day 29 in participants with severely reduced kidney function who are hospitalized for coronavirus disease 2019 (COVID-19).

What is the current status of trial NCT04745351?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 249 participants. The study started on 2021-03-31. Estimated completion is 2022-05-24.

What interventions are being tested in trial NCT04745351?

The interventions under investigation include: Standard of Care (DRUG), Remdesivir (DRUG), RDV Placebo (DRUG).

Who is sponsoring clinical trial NCT04745351?

This trial is sponsored by Gilead Sciences, which has 504 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.