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NCT06067555 · ClinicalTrials.gov registry record · Early Phase 1

Intradermal Influenza Vaccination

A Early Phase 1 study of Vaccine Reaction, sponsored by Yale University.

Recruiting
Registry status
Early Phase 1
Development phase
249
Enrollment target
1
Study location

NCT06067555 is a Early Phase 1 study of Vaccine Reaction that is actively recruiting participants, run by Yale University. The registered enrollment target is 249 participants, above the 81-participant average among 4 other Vaccine Reaction trials with a reported enrollment target (207% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT06067555, a Early Phase 1 study of Vaccine Reaction, is actively recruiting participants, sponsored by Yale University.

RECRUITING
Registry status
Early Phase 1
Development phase
249 participants
Enrollment target
1
Study location

Study Summary

The goal of this study is to characterize the immune response, both innate and adaptive, as well as locally and systemic, to intradermal (ID) vaccination in healthy individuals. The intervention involves intradermal administration of an FDA-approved intramuscular seasonal influenza vaccine, using an FDA-approved device MicronJet. Investigators will measure antibody titers, cell subtypes, and multi-omic profiles, by collecting skin and peripheral blood at baseline and at several time points after vaccination. The primary objective is to identify baseline correlates of immune response in the skin and peripheral blood to the seasonal influenza vaccine. The investigators secondary goals are to describe the inflammatory response in the skin over time.

Conditions Studied

Interventions

  • DEVICE MicronJet
  • BIOLOGICAL Fluzone® Quadrivalent
  • OTHER Bacteriostatic Saline

Study Locations (1)

Connecticut

  • Church Street Research Unit - New Haven

Trial Details

FieldValue
Enrollment Target 249 participants
Start Date 2024-01-24
Est. Completion 2026-05
Phase Early Phase 1

Sponsor

Yale University

1,492 total trials

What the Registry Record Tells You About NCT06067555

The ClinicalTrials.gov registry entry for NCT06067555 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 249 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 81-participant average among 4 other Vaccine Reaction trials with a reported enrollment target (207% higher). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Vaccine Reaction appearing as the primary indexed condition, and to 3 interventions - of which MicronJet is the first listed.

NCT06067555 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT06067555 about?

NCT06067555 is a clinical study titled "Intradermal Influenza Vaccination". The goal of this study is to characterize the immune response, both innate and adaptive, as well as locally and systemic, to intradermal (ID) vaccination in healthy individuals. The intervention involves intradermal administration of an FDA-approved intramuscular seasonal influenza vaccine, using an...

What is the current status of trial NCT06067555?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 249 participants. The study started on 2024-01-24. Estimated completion is 2026-05.

What conditions does trial NCT06067555 study?

This clinical trial studies the following conditions: Vaccine Reaction.

What interventions are being tested in trial NCT06067555?

The interventions under investigation include: MicronJet (DEVICE), Fluzone® Quadrivalent (BIOLOGICAL), Bacteriostatic Saline (OTHER).

Who is sponsoring clinical trial NCT06067555?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06067555 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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