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NCT04740671 · ClinicalTrials.gov registry record · Phase 3
A Phase 3 Study to Compare the Efficacy and Safety of HLX04-O with Ranibizumab in Subjects with WAMD
A Phase 3 study, sponsored by Shanghai Henlius Biotech.
- Completed
- Registry status
- Phase 3
- Development phase
- 410
- Enrollment target
NCT04740671: Completed Phase 3 study, sponsored by Shanghai Henlius Biotech.
NCT04740671 is a Phase 3 study that has completed, run by Shanghai Henlius Biotech. The registered enrollment target is 410 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04740671, a Phase 3 study, has completed, sponsored by Shanghai Henlius Biotech.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 410 participants
- Enrollment target
Study Summary
This study will compare the efficacy and safety of HLX04-O administered by intravitreal injection (IVT) with ranibizumab in patients with active wAMD.
Primary Outcome
Detailed Outcome Measure will be defined in the Statistical Analysis Plan
Interventions
- DRUG ranibizumab
- DRUG HLX04-O
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 410 participants |
| Start Date | 2021-07-01 |
| Est. Completion | 2024-12-31 |
| Phase | Phase 3 |
What the finished NCT04740671 record still lists
NCT04740671 is an interventional study that assigns participants to a tested intervention. The registered 410 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (47% lower).
The record links to 0 conditions, and to 2 interventions - of which ranibizumab is the first listed.
NCT04740671 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04740671 about?
NCT04740671 is a clinical study titled "A Phase 3 Study to Compare the Efficacy and Safety of HLX04-O with Ranibizumab in Subjects with WAMD". This study will compare the efficacy and safety of HLX04-O administered by intravitreal injection (IVT) with ranibizumab in patients with active wAMD.
What is the current status of trial NCT04740671?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 410 participants. The study started on 2021-07-01. Estimated completion is 2024-12-31.
What interventions are being tested in trial NCT04740671?
The interventions under investigation include: ranibizumab (DRUG), HLX04-O (DRUG).
Who is sponsoring clinical trial NCT04740671?
This trial is sponsored by Shanghai Henlius Biotech, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04740671's enrollment target sits among peer trials
410 909th of 2000 higher than 1,090 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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