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NCT04735471 · ClinicalTrials.gov registry record · Phase 1
A Phase 1 Study of ADI-001 in B Cell Malignancies
A Phase 1 study, sponsored by Adicet Therapeutics.
- Terminated
- Registry status
- Phase 1
- Development phase
- 34
- Enrollment target
NCT04735471: Clinical Trial Phase 1 study, sponsored by Adicet Therapeutics.
NCT04735471 is a Phase 1 study that was terminated before completion, run by Adicet Therapeutics. The registered enrollment target is 34 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (43% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04735471, a Phase 1 study, was terminated before completion, sponsored by Adicet Therapeutics.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 34 participants
- Enrollment target
Study Summary
This is a Phase 1 dose escalation study following a 3+3 study design. The purpose of this study is to evaluate the safety and efficacy of ADI-001 in patients with B cell malignancies.
Primary Outcome
This primary endpoint will be used to determine the Maximum Tolerated Dose (MTD) or Maximum Assessed dose (MAD).
Interventions
- DRUG Cyclophosphamide
- DRUG Fludarabine
- GENETIC ADI-001
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 34 participants |
| Start Date | 2021-03-04 |
| Est. Completion | 2025-02-03 |
| Phase | Phase 1 |
Why NCT04735471 stopped before completion
NCT04735471 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 34 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (43% lower).
The record links to 0 conditions, and to 3 interventions - of which Cyclophosphamide is the first listed.
NCT04735471 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04735471 about?
NCT04735471 is a clinical study titled "A Phase 1 Study of ADI-001 in B Cell Malignancies". This is a Phase 1 dose escalation study following a 3+3 study design. The purpose of this study is to evaluate the safety and efficacy of ADI-001 in patients with B cell malignancies.
What is the current status of trial NCT04735471?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 34 participants. The study started on 2021-03-04. Estimated completion is 2025-02-03.
What interventions are being tested in trial NCT04735471?
The interventions under investigation include: Cyclophosphamide (DRUG), Fludarabine (DRUG), ADI-001 (GENETIC).
Who is sponsoring clinical trial NCT04735471?
This trial is sponsored by Adicet Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04735471's enrollment target sits among peer trials
34 1273rd of 2000 higher than 721 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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