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NCT04725409 · ClinicalTrials.gov registry record
Neural Correlates of Psychiatric Disorders
A clinical trial of Memory Disorders and Psychiatric Disorder, sponsored by Vanderbilt University Medical Center.
- Recruiting
- Registry status
- 100
- Enrollment target
- 1
- Study location
NCT04725409: Recruiting study of Memory Disorders and Psychiatric Disorder, sponsored by Vanderbilt University Medical Center.
NCT04725409 is a study of Memory Disorders and Psychiatric Disorder that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 100 participants, below the 252-participant average among 9 other Memory Disorders trials with a reported enrollment target (60% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04725409, a study of Memory Disorders and Psychiatric Disorder, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.
- RECRUITING
- Registry status
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
This ClincialTrials.gov record originally corresponded to the protocol approved under IRB # 202370. The study was expanded to include stimulation and recordings approved under new IRB #211037. The participant data originally acquired from IRB# 202370 will be included in this new record: This study seeks to better understand the neural activity underlying neuro cognitive disorders. Resting state local field potential recordings will be collected from medically refractory epilepsy patients implanted with depth electrodes for seizure localization, and metrics of neural activity will be correlated with psychiatric symptoms as measured from questionnaires. Subjects will also participate in neuro cognitive tasks while neural recordings are performed, and/or receive neural stimulation through implanted depth electrodes. A better understanding of disordered neural activity underlying neuropsychiatric disorders may additionally contribute to novel methods for diagnosing, treating, and preventing these diseases.
Primary Outcome
The Center for Epidemiologic Studies Depression Scale - Revised (CESD-R) is a commonly used and well validated depression screening tool consisting of 20 questions. Scores range from 0 to 60 and a score of 16 or above indicates a risk for clinical depression. CESD-R scores will be correlated with resting state measures of neural activity and connectivity
Conditions Studied
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2021-03-31 |
| Est. Completion | 2026-02 |
What NCT04725409 shows while recruiting
NCT04725409 is an observational study that tracks outcomes without assigning an intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 252-participant average among 9 other Memory Disorders trials with a reported enrollment target (60% lower).
The record links to 2 conditions, with Memory Disorders appearing as the primary indexed condition, and to 0 interventions.
NCT04725409 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT04725409 about?
NCT04725409 is a clinical study titled "Neural Correlates of Psychiatric Disorders". This ClincialTrials.gov record originally corresponded to the protocol approved under IRB # 202370. The study was expanded to include stimulation and recordings approved under new IRB #211037. The participant data originally acquired from IRB# 202370 will be included in this new record: This study ...
What is the current status of trial NCT04725409?
This trial is currently recruiting. The enrollment target is 100 participants. The study started on 2021-03-31. Estimated completion is 2026-02.
What conditions does trial NCT04725409 study?
This clinical trial studies the following conditions: Memory Disorders, Psychiatric Disorder.
Who is sponsoring clinical trial NCT04725409?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04725409 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Memory Disorders
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04725409's enrollment target sits among peer trials
100 6th of 9 higher than 4 of 9 other Memory Disorders trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Memory Disorders trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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