Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04721886 · ClinicalTrials.gov registry record · Early Phase 1
Contrast-Enhanced Ultrasound Scan for the Estimation of Tissue Pressure in Patients With Breast Cancer
A Early Phase 1 study, sponsored by Thomas Jefferson University.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 25
- Enrollment target
NCT04721886: Completed Early Phase 1 study, sponsored by Thomas Jefferson University.
NCT04721886 is a Early Phase 1 study that has completed, run by Thomas Jefferson University. The registered enrollment target is 25 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04721886, a Early Phase 1 study, has completed, sponsored by Thomas Jefferson University.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 25 participants
- Enrollment target
Study Summary
This clinical trial studies the use of contrast-enhanced ultrasound (CEUS) in estimating tissue pressure in patients with breast cancer. Diagnostic procedures, such as CEUS, may help estimate tissue pressure noninvasively.
Primary Outcome
Pearson's correlation coefficients will be computed between SHAPE results and direct IFP measurements by Stryker compartment pressure monitoring system. A Pearson's correlation coefficient above 0.5 will be considered a successful outcome.
Interventions
- PROCEDURE Ultrasonsgraphy
- DRUG Perflutren Lipid Microcpheres
- PROCEDURE Contrast - Enhanced Ultrasound
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2020-11-24 |
| Est. Completion | 2023-07-11 |
| Phase | Early Phase 1 |
What the finished NCT04721886 record still lists
NCT04721886 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (53% lower).
The record links to 0 conditions, and to 3 interventions - of which Ultrasonsgraphy is the first listed.
NCT04721886 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04721886 about?
NCT04721886 is a clinical study titled "Contrast-Enhanced Ultrasound Scan for the Estimation of Tissue Pressure in Patients With Breast Cancer". This clinical trial studies the use of contrast-enhanced ultrasound (CEUS) in estimating tissue pressure in patients with breast cancer. Diagnostic procedures, such as CEUS, may help estimate tissue pressure noninvasively.
What is the current status of trial NCT04721886?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 25 participants. The study started on 2020-11-24. Estimated completion is 2023-07-11.
What interventions are being tested in trial NCT04721886?
The interventions under investigation include: Ultrasonsgraphy (PROCEDURE), Perflutren Lipid Microcpheres (DRUG), Contrast - Enhanced Ultrasound (PROCEDURE).
Who is sponsoring clinical trial NCT04721886?
This trial is sponsored by Thomas Jefferson University, which has 292 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04721886's enrollment target sits among peer trials
25 1000th of 2000 higher than 965 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01166854 · 25 participants
Characterization of Familial Myopathy and Paget Disease of Bone
- NCT01913106 · 25 participants · Phase 1
HSV-tk + Valacyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer
- NCT02138669 · 25 participants · NA
Intacs Prescription Inserts for Keratoconus Patients
- NCT02174549 · 25 participants · Phase 1
Dose-defining Study of Tirapazamine Combined With Embolization in Liver Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI