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NCT04716699 · ClinicalTrials.gov registry record · Phase 1
Systemic and Local Levels of Lidocaine During Surgery for the Removal of Glioblastoma
A Phase 1 study, sponsored by University of California, Davis.
- Completed
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
NCT04716699: Completed Phase 1 study, sponsored by University of California, Davis.
NCT04716699 is a Phase 1 study that has completed, run by University of California, Davis. The registered enrollment target is 12 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04716699, a Phase 1 study, has completed, sponsored by University of California, Davis.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
Study Summary
This clinical trial measures the amount and effect of lidocaine injected into patients with glioblastoma while they are undergoing surgical removal of their brain tumors. Lidocaine is a substance used to relieve pain by blocking signals at the nerve endings in skin. Information gained from this study may help researchers come up with new treatments to help patients with glioblastomas in the future.
Primary Outcome
Analysis is mainly descriptive and will be mainly done by Lidocaine analysis lab. Will report the mean and standard deviation of concentration of lidocaine in the tumor and blood at 3 time points. The pharmacokinetics of lidocaine within the tumor will be summarized using the means, and standard pharmacokinetics parameters will be reported (maximum concentration, time of maximum concentration, and area under the curve). If applicable, will use mixed effects model to summarize trajectories of cha
Interventions
- PROCEDURE Biospecimen Collection
- DRUG Lidocaine
- PROCEDURE Resection
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2021-01-20 |
| Est. Completion | 2022-01-24 |
| Phase | Phase 1 |
What the finished NCT04716699 record still lists
NCT04716699 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 3 interventions - of which Biospecimen Collection is the first listed.
NCT04716699 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04716699 about?
NCT04716699 is a clinical study titled "Systemic and Local Levels of Lidocaine During Surgery for the Removal of Glioblastoma". This clinical trial measures the amount and effect of lidocaine injected into patients with glioblastoma while they are undergoing surgical removal of their brain tumors. Lidocaine is a substance used to relieve pain by blocking signals at the nerve endings in skin. Information gained from this stud...
What is the current status of trial NCT04716699?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2021-01-20. Estimated completion is 2022-01-24.
What interventions are being tested in trial NCT04716699?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Lidocaine (DRUG), Resection (PROCEDURE).
Who is sponsoring clinical trial NCT04716699?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04716699's enrollment target sits among peer trials
12 1852nd of 2000 higher than 90 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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