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NCT04710862 · ClinicalTrials.gov registry record · NA
The Effects of Respiratory Training on Voice
A NA study, sponsored by Syracuse University.
- Completed
- Registry status
- NA
- Development phase
- 27
- Enrollment target
NCT04710862: Completed NA study, sponsored by Syracuse University.
NCT04710862 is a NA study that has completed, run by Syracuse University. The registered enrollment target is 27 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04710862, a NA study, has completed, sponsored by Syracuse University.
- COMPLETED
- Registry status
- NA
- Development phase
- 27 participants
- Enrollment target
Study Summary
Primary muscle tension dysphonia is a voice disorder that involves excessive and poorly coordinated muscle activity affecting multiple subsystems that are involved in speech production, in the absence of structural or neurologic abnormalities of the larynx. Primary muscle tension dysphonia (MTD) is one of the most common forms of voice disorders, accounting for at least 40% of patients seen in voice clinics. Perceptually the voice sounds hoarse and strained, with reduced loudness and pitch range, and people with MTD find speaking very effortful and fatiguing. The physiological abnormalities that characterize MTD are considered multifactorial, and include over-activity of muscles in and around the larynx, laryngeal constriction patterns, and abnormal speech breathing patterns. However, standard treatment approaches for MTD primarily address laryngeal function, including repositioning of laryngeal structures, reducing activity in the intrinsic and extrinsic laryngeal muscles, and altering vibratory patterns. Although voice improvement may follow these treatments, many people with MTD show recurrence of voice problems after only a few months, and some do not improve with treatment. These findings highlight the need for alternative treatments that address the respiratory contributions to MTD, which directly affect the phonatory system. The goal of this project is to compare the effects of two respiratory-based training conditions in people with MTD. A randomized group design will be implemented to determine the respiratory and acoustic effects of each condition. We will determine the effects of each condition immediately after and then 3 and 6 months after training completion to assess short- and long-term training effects. We propose that respiratory training will have a positive effect on related laryngeal behavior and voice. The proposed project has the potential to substantially advance the evidence-based treatment options for MTD, providing a vital step toward redu
Primary Outcome
Average level of lung volume at which speech breaths are initiated, expressed in percent vital capacity relative to resting expiratory level.
Interventions
- BEHAVIORAL Breathing training without a device
- BEHAVIORAL Breathing training with a device
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2021-05-12 |
| Est. Completion | 2024-09-23 |
| Phase | NA |
What the finished NCT04710862 record still lists
NCT04710862 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Breathing training without a device is the first listed.
NCT04710862 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04710862 about?
NCT04710862 is a clinical study titled "The Effects of Respiratory Training on Voice". Primary muscle tension dysphonia is a voice disorder that involves excessive and poorly coordinated muscle activity affecting multiple subsystems that are involved in speech production, in the absence of structural or neurologic abnormalities of the larynx. Primary muscle tension dysphonia (MTD) is ...
What is the current status of trial NCT04710862?
This trial is currently completed. It is a NA study. The enrollment target is 27 participants. The study started on 2021-05-12. Estimated completion is 2024-09-23.
What interventions are being tested in trial NCT04710862?
The interventions under investigation include: Breathing training without a device (BEHAVIORAL), Breathing training with a device (BEHAVIORAL).
Who is sponsoring clinical trial NCT04710862?
This trial is sponsored by Syracuse University, which has 31 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04710862's enrollment target sits among peer trials
27 1708th of 2000 higher than 291 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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