Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04686604 · ClinicalTrials.gov registry record · NA
PRagmatic Trial Of Messaging to Providers About Treatment of Heart Failure in the Inpatient Setting
A NA study, sponsored by Yale University.
- Completed
- Registry status
- NA
- Development phase
- 1,012
- Enrollment target
NCT04686604: Completed NA study, sponsored by Yale University.
NCT04686604 is a NA study that has completed, run by Yale University. The registered enrollment target is 1,012 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (28% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04686604, a NA study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- NA
- Development phase
- 1,012 participants
- Enrollment target
Study Summary
A randomized single-blind interventional trial to test the effectiveness of an electronic medical record-based best practice alert recommending evidence-based medical therapies versus usual care in inpatient adult patients presenting with heart failure with reduced ejection fraction.
Primary Outcome
Assessed as an increase in the number of prescribed targeted evidence-based medical therapies for HFrEF. Evidence-based medical therapies include: beta-blockers, ACEi/ARBs/ARNIs, MRAs, and SGLT2is.
Interventions
- OTHER Best practice alert for the notification of patient HFrEF and recommended evidence-based medical therapies (NO drugs are being administered in this trial)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,012 participants |
| Start Date | 2021-07-07 |
| Est. Completion | 2023-06-30 |
| Phase | NA |
What the finished NCT04686604 record still lists
NCT04686604 is an interventional study that assigns participants to a tested intervention. Its 1,012 participants enrollment target places it among the larger protocols in the corpus, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (28% lower).
The record links to 0 conditions, and to 1 intervention - of which Best practice alert for the notification of patient HFrEF and recommended evidence-based medical therapies (NO drugs are being administered in this trial) is the first listed.
NCT04686604 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04686604 about?
NCT04686604 is a clinical study titled "PRagmatic Trial Of Messaging to Providers About Treatment of Heart Failure in the Inpatient Setting". A randomized single-blind interventional trial to test the effectiveness of an electronic medical record-based best practice alert recommending evidence-based medical therapies versus usual care in inpatient adult patients presenting with heart failure with reduced ejection fraction.
What is the current status of trial NCT04686604?
This trial is currently completed. It is a NA study. The enrollment target is 1,012 participants. The study started on 2021-07-07. Estimated completion is 2023-06-30.
What interventions are being tested in trial NCT04686604?
The interventions under investigation include: Best practice alert for the notification of patient HFrEF and recommended evidence-based medical therapies (NO drugs are being administered in this trial) (OTHER).
Who is sponsoring clinical trial NCT04686604?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04686604's enrollment target sits among peer trials
1,012 106th of 2000 higher than 1,895 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT06146738 · 1,015 participants
The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203)
- NCT06608823 · 1,016 participants · NA
ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™
- NCT07191782 · 1,008 participants · NA
Examining the Efficacy of the PRAISE With Coaching Program
- NCT06549595 · 1,018 participants · Phase 3
A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI