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NCT04682353 · ClinicalTrials.gov registry record · Phase 1

A Study to Evaluate the Pharmacokinetics (PK) of Medroxyprogesterone Acetate Following an Injection of TV-46046 in Healthy Women of Reproductive Age

A Phase 1 study of Contraception, sponsored by Teva Branded Pharmaceutical Products R&D.

Completed
Registry status
Phase 1
Development phase
60
Enrollment target
3
Study locations

NCT04682353 is a Phase 1 study of Contraception that has completed, run by Teva Branded Pharmaceutical Products R&D. The registered enrollment target is 60 participants, below the 454-participant average among 72 other Contraception trials with a reported enrollment target (87% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT04682353, a Phase 1 study of Contraception, has completed, sponsored by Teva Branded Pharmaceutical Products R&D.

COMPLETED
Registry status
Phase 1
Development phase
60 participants
Enrollment target
3
Study locations

Study Summary

The primary objective of this study is to evaluate and compare the pharmacokinetic profile of Medroxyprogesterone acetate following subcutaneous administration of 3 different doses of TV-46046 and a dose of Depo-subQ Provera in healthy female participants. The secondary objectives of the study are to evaluate and compare the safety, local tolerability, and acceptability of a subcutaneous injection of 3 different doses of TV-46046 and a dose of Depo-subQ Provera in healthy female participants. The total duration of the study for each participant is expected to be up to 19.5 months.

Conditions Studied

Interventions

  • DRUG TV-46046
  • DRUG Depo-subQ Provera

Study Locations (3)

California

  • Teva Investigational Site 14002 - Cypress

Texas

  • Teva Investigational Site 14003 - San Antonio

Other

  • Teva Investigational Site 18001 - Santo Domingo

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2020-12-14
Est. Completion 2023-01-12
Phase Phase 1

What the Registry Record Tells You About NCT04682353

The ClinicalTrials.gov registry entry for NCT04682353 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 454-participant average among 72 other Contraception trials with a reported enrollment target (87% lower). The listed sponsor is Teva Branded Pharmaceutical Products R&D, which has 167 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Contraception appearing as the primary indexed condition, and to 2 interventions - of which TV-46046 is the first listed.

NCT04682353 reports 3 study locations spanning 3 distinct geographic areas - top geographies include California, Texas, Other.

Frequently Asked Questions

What is clinical trial NCT04682353 about?

NCT04682353 is a clinical study titled "A Study to Evaluate the Pharmacokinetics (PK) of Medroxyprogesterone Acetate Following an Injection of TV-46046 in Healthy Women of Reproductive Age". The primary objective of this study is to evaluate and compare the pharmacokinetic profile of Medroxyprogesterone acetate following subcutaneous administration of 3 different doses of TV-46046 and a dose of Depo-subQ Provera in healthy female participants. The secondary objectives of the study are ...

What is the current status of trial NCT04682353?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2020-12-14. Estimated completion is 2023-01-12.

What conditions does trial NCT04682353 study?

This clinical trial studies the following conditions: Contraception.

What interventions are being tested in trial NCT04682353?

The interventions under investigation include: TV-46046 (DRUG), Depo-subQ Provera (DRUG).

Who is sponsoring clinical trial NCT04682353?

This trial is sponsored by Teva Branded Pharmaceutical Products R&D, which has 167 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04682353 being conducted?

This trial has 3 study locations across California, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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