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NCT04662060 · ClinicalTrials.gov registry record · Phase 2

COVID-19 Outpatient Pragmatic Platform Study (COPPS) - Acebilustat Sub-Protocol

A Phase 2 study, sponsored by Stanford University.

Completed
Registry status
Phase 2
Development phase
120
Enrollment target

NCT04662060: Completed Phase 2 study, sponsored by Stanford University.

NCT04662060 is a Phase 2 study that has completed, run by Stanford University. The registered enrollment target is 120 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (10% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT04662060, a Phase 2 study, has completed, sponsored by Stanford University.

COMPLETED
Registry status
Phase 2
Development phase
120 participants
Enrollment target

Study Summary

The overall objective of this study is to efficiently evaluate the clinical efficacy and safety of different investigational therapeutics among adults who have COVID-19 but are not yet sick enough to require hospitalization. The overall hypothesis is that through an adaptive trial design, potential effective therapies (single and combination) may be identified for this group of patients. COVID-19 Outpatient Pragmatic Platform Study (COPPS) is a pragmatic platform protocol designed to evaluate COVID-19 treatments by assessing their ability to reduce viral shedding (Viral Domain) or improve clinical outcomes (Clinical Domain). To be included into the platform, every investigational product will collect data for both Domain primary endpoints. Individual treatments to be evaluated in the platform will be described in separate sub-protocols.

Primary Outcome

Time from randomization to sustained symptom resolution assessed over a 28-day period. Resolution is defined as the first day where no symptoms are self-reported on all succeeding days through and including day 28, not including sense of taste or smell, and defining recovery for fatigue and cough as mild or none.

Interventions

  • DRUG Placebo
  • DRUG Acebilustat

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2021-04-23
Est. Completion 2023-02-02
Phase Phase 2
Stanford University

1,744 total trials

What the finished NCT04662060 record still lists

NCT04662060 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (10% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04662060 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04662060 about?

NCT04662060 is a clinical study titled "COVID-19 Outpatient Pragmatic Platform Study (COPPS) - Acebilustat Sub-Protocol". The overall objective of this study is to efficiently evaluate the clinical efficacy and safety of different investigational therapeutics among adults who have COVID-19 but are not yet sick enough to require hospitalization. The overall hypothesis is that through an adaptive trial design, potential ...

What is the current status of trial NCT04662060?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 120 participants. The study started on 2021-04-23. Estimated completion is 2023-02-02.

What interventions are being tested in trial NCT04662060?

The interventions under investigation include: Placebo (DRUG), Acebilustat (DRUG).

Who is sponsoring clinical trial NCT04662060?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04662060's enrollment target sits among peer trials

120 569th of 2000 higher than 1,383 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04662060, the US trial registry maintained by the National Library of Medicine. NCT04662060 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.