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NCT04658628 · ClinicalTrials.gov registry record
Brain Imaging Biomarkers for Response to Spinal Cord Stimulation in Patients With Chronic Low Back Pain
A clinical trial of Chronic Low Back Pain, sponsored by University of California, Los Angeles.
- Recruiting
- Registry status
- 42
- Enrollment target
- 1
- Study location
NCT04658628: Recruiting study of Chronic Low Back Pain, sponsored by University of California, Los Angeles.
NCT04658628 is a study of Chronic Low Back Pain that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 42 participants, below the 591-participant average among 71 other Chronic Low Back Pain trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04658628, a study of Chronic Low Back Pain, is actively recruiting participants, sponsored by University of California, Los Angeles.
- RECRUITING
- Registry status
- 42 participants
- Enrollment target
- 1
- Study location
Study Summary
In this protocol, "Brain imaging biomarkers for response to Spinal Cord Stimulation in patients with chronic low back pain," the investigators plan to perform brain mapping studies in 42 patients who are undergoing spinal cord stimulation (SCS) for chronic low back pain (CLBP) as part of the participants normal clinical care during a 2-year period. This imagining study is completed for research purposes. There is no standard of care imaging for the participants. This study requires two visits in total. During the baseline visit, participants will undergo imaging acquisition protocol and corresponding assessments. Participants will have another follow-up visit (potentially remotely) for final assessments two weeks after the SCS treatment. The objective of the study is to investigate potential imaging biomarkers that can predict response to the SCS treatment. Specifically, the investigators hypothesize that the connectivity of a certain region of the brain (specifically the subgenual cingulate) prior to SCS may serve as a possible pre-operative imaging-based biomarker on response to SCS. The findings of the study may further enhance investigators understanding of the connectivity between brain areas that are critical to the therapeutic response to SCS in CLBP patients and that can be used as a putative biomarker to select patients who may respond to SCS.
Primary Outcome
The visual analog scale for pain is a continuous horizontal scale of length 100mm with the extremes of pain expressed on either end (left = no pain, right = worst pain).
Conditions Studied
Study Locations (1)
California
- University of California Los Angeles - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2021-01-22 |
| Est. Completion | 2027-11 |
What NCT04658628 shows while recruiting
NCT04658628 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 591-participant average among 71 other Chronic Low Back Pain trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Chronic Low Back Pain appearing as the primary indexed condition, and to 0 interventions.
NCT04658628 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04658628 about?
NCT04658628 is a clinical study titled "Brain Imaging Biomarkers for Response to Spinal Cord Stimulation in Patients With Chronic Low Back Pain". In this protocol, "Brain imaging biomarkers for response to Spinal Cord Stimulation in patients with chronic low back pain," the investigators plan to perform brain mapping studies in 42 patients who are undergoing spinal cord stimulation (SCS) for chronic low back pain (CLBP) as part of the partici...
What is the current status of trial NCT04658628?
This trial is currently recruiting. The enrollment target is 42 participants. The study started on 2021-01-22. Estimated completion is 2027-11.
What conditions does trial NCT04658628 study?
This clinical trial studies the following conditions: Chronic Low Back Pain.
Who is sponsoring clinical trial NCT04658628?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04658628 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Low Back Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04658628's enrollment target sits among peer trials
42 52nd of 71 higher than 19 of 71 other Chronic Low Back Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Low Back Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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