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NCT04646044 · ClinicalTrials.gov registry record · Phase 1

A Placebo Controlled Trial of Bempegaldesleukin (BEMPEG; NKTR-214) With Standard of Care in Patients With Mild COVID-19

A Phase 1 study, sponsored by Nektar Therapeutics.

Completed
Registry status
Phase 1
Development phase
30
Enrollment target

NCT04646044 is a Phase 1 study that has completed, run by Nektar Therapeutics. The registered enrollment target is 30 participants.

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The verdict

NCT04646044, a Phase 1 study, has completed, sponsored by Nektar Therapeutics.

COMPLETED
Registry status
Phase 1
Development phase
30 participants
Enrollment target

Study Summary

The main purpose of this phase-1b, multicenter, randomized double-blind, placebo-controlled, trial is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of bempegaldesleukin (BEMPEG; NKTR-214) in combination with standard of care (SOC) in adult patients with mild COVID-19 (coronavirus disease 2019). The trial will also define the recommended phase 2 dose (RP2D) of bempegaldesleukin in patients with mild COVID-19.

Interventions

  • OTHER Placebo
  • DRUG Standard of Care
  • DRUG Bempegaldesleukin

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2020-11-13
Est. Completion 2021-05-18
Phase Phase 1

Sponsor

Nektar Therapeutics

37 total trials

What the Registry Record Tells You About NCT04646044

The ClinicalTrials.gov registry entry for NCT04646044 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Nektar Therapeutics, which has 37 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT04646044 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04646044 about?

NCT04646044 is a clinical study titled "A Placebo Controlled Trial of Bempegaldesleukin (BEMPEG; NKTR-214) With Standard of Care in Patients With Mild COVID-19". The main purpose of this phase-1b, multicenter, randomized double-blind, placebo-controlled, trial is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of bempegaldesleukin (BEMPEG; NKTR-214) in combination with standard of care (SOC) in adult patients with mild COVID-19 (...

What is the current status of trial NCT04646044?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2020-11-13. Estimated completion is 2021-05-18.

What interventions are being tested in trial NCT04646044?

The interventions under investigation include: Placebo (OTHER), Standard of Care (DRUG), Bempegaldesleukin (DRUG).

Who is sponsoring clinical trial NCT04646044?

This trial is sponsored by Nektar Therapeutics, which has 37 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.