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NCT04642989 · ClinicalTrials.gov registry record · NA
The Effect of Facial Effleurage on Acute Rhinosinusitis
A NA study of Rhinosinusitis Acute, sponsored by Edward Via Virginia College of Osteopathic Medicine.
- Completed
- Registry status
- NA
- Development phase
- 138
- Enrollment target
- 1
- Study location
NCT04642989: Completed NA study of Rhinosinusitis Acute, sponsored by Edward Via Virginia College of Osteopathic Medicine.
NCT04642989 is a NA study of Rhinosinusitis Acute that has completed, run by Edward Via Virginia College of Osteopathic Medicine. The registered enrollment target is 138 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04642989, a NA study of Rhinosinusitis Acute, has completed, sponsored by Edward Via Virginia College of Osteopathic Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 138 participants
- Enrollment target
- 1
- Study location
Study Summary
Rhinosinusitis accounts for 12% of the total antibiotic prescriptions filled in the United States annually; however, the majority of rhinosinusitis cases have been proposed to have a viral etiology, or are capable of spontaneously resolving. This overuse of antibiotics is contributing to the development of antibiotic-resistant human pathogenic bacteria, and increasing patient mortality to previously easily cured diseases. This is also causing an unnecessary financial burden especially for uninsured, rural families. Facial Effleurage (FE) is an osteopathic manipulative therapy that allows physicians an alternative therapy to prescribing antibiotics; however, the only scientific literature on the technique is weak in design and execution. This will be a randomized, placebo-controlled clinical trial to test the ability of FE to reduce symptom severity over time, reduce the cellular infiltrate into the nasal cavity, and to more quickly resolve the symptoms of rhinosinusitis compared to antibiotic treatment. This methodical approach to the efficacy of FE has the potential to impact the treatment recommendations of physicians immediately, and to convince more physicians to prescribe less antibiotics and rely more heavily on FE.
Primary Outcome
SinoNasal Outcome Test-20 questionnaire. The scale is from 0-100 where 0 indicates no symptoms and 100 is the worst symptoms possible.
Conditions Studied
Interventions
- DRUG Antibiotics
- OTHER Sham Treatment
- OTHER Facial Effleurage
Study Locations (1)
South Carolina
- Edward Via College of Osteopathic Medicine - Spartanburg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 138 participants |
| Start Date | 2018-09-01 |
| Est. Completion | 2020-09-01 |
| Phase | NA |
What the finished NCT04642989 record still lists
NCT04642989 is an interventional study that assigns participants to a tested intervention. The registered 138 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Rhinosinusitis Acute appearing as the primary indexed condition, and to 3 interventions - of which Antibiotics is the first listed.
NCT04642989 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT04642989 about?
NCT04642989 is a clinical study titled "The Effect of Facial Effleurage on Acute Rhinosinusitis". Rhinosinusitis accounts for 12% of the total antibiotic prescriptions filled in the United States annually; however, the majority of rhinosinusitis cases have been proposed to have a viral etiology, or are capable of spontaneously resolving. This overuse of antibiotics is contributing to the develop...
What is the current status of trial NCT04642989?
This trial is currently completed. It is a NA study. The enrollment target is 138 participants. The study started on 2018-09-01. Estimated completion is 2020-09-01.
What conditions does trial NCT04642989 study?
This clinical trial studies the following conditions: Rhinosinusitis Acute.
What interventions are being tested in trial NCT04642989?
The interventions under investigation include: Antibiotics (DRUG), Sham Treatment (OTHER), Facial Effleurage (OTHER).
Who is sponsoring clinical trial NCT04642989?
This trial is sponsored by Edward Via Virginia College of Osteopathic Medicine, which has 19 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04642989 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04642989's enrollment target sits among peer trials
138 720th of 2000 higher than 1,279 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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