Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04634669 · ClinicalTrials.gov registry record · Phase 2

Open-Label Safety Study of AXS-05 in Subjects With TRD (EVOLVE)

A Phase 2 study, sponsored by Axsome Therapeutics.

Terminated
Registry status
Phase 2
Development phase
181
Enrollment target

NCT04634669 is a Phase 2 study that was terminated before completion, run by Axsome Therapeutics. The registered enrollment target is 181 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04634669, a Phase 2 study, was terminated before completion, sponsored by Axsome Therapeutics.

TERMINATED
Registry status
Phase 2
Development phase
181 participants
Enrollment target

Study Summary

This study is a multi-center, open-label trial to evaluate the long-term safety and efficacy of AXS-05 in subjects with major depressive disorder with prior treatment failures

Interventions

  • DRUG AXS-05 (dextromethorphan-bupropion)

Trial Details

FieldValue
Enrollment Target 181 participants
Start Date 2020-09-23
Est. Completion 2022-03-04
Phase Phase 2

Sponsor

Axsome Therapeutics

28 total trials

What the Registry Record Tells You About NCT04634669

The ClinicalTrials.gov registry entry for NCT04634669 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 181 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Axsome Therapeutics, which has 28 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which AXS-05 (dextromethorphan-bupropion) is the first listed.

NCT04634669 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04634669 about?

NCT04634669 is a clinical study titled "Open-Label Safety Study of AXS-05 in Subjects With TRD (EVOLVE)". This study is a multi-center, open-label trial to evaluate the long-term safety and efficacy of AXS-05 in subjects with major depressive disorder with prior treatment failures

What is the current status of trial NCT04634669?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 181 participants. The study started on 2020-09-23. Estimated completion is 2022-03-04.

What interventions are being tested in trial NCT04634669?

The interventions under investigation include: AXS-05 (dextromethorphan-bupropion) (DRUG).

Who is sponsoring clinical trial NCT04634669?

This trial is sponsored by Axsome Therapeutics, which has 28 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.