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NCT04633343 · ClinicalTrials.gov registry record · NA
Effects of Different Tidal Volume Ventilation Strategies on Fontan Flow and Hemodynamics
A NA study, sponsored by Stanford University.
- Completed
- Registry status
- NA
- Development phase
- 12
- Enrollment target
NCT04633343: Completed NA study, sponsored by Stanford University.
NCT04633343 is a NA study that has completed, run by Stanford University. The registered enrollment target is 12 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04633343, a NA study, has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
Study Summary
In patients with Fontan circulation blood is not pumped to the lungs from a ventricle. Instead the superior vena cava and inferior vena cava is connected to the pulmonary artery and blood flow to the lungs occurs passively along this Fontan pathway. This passive blood flow to the lungs occurs best when the patient is breathing on their own (spontaneous ventilation). However for certain surgeries and procedures patients need to have an endotracheal tube inserted and need to be muscle relaxed and receive positive pressure ventilation. Prior studies have shown that positive pressure ventilation can reduce blood flow to the lungs and consequently blood returning to the heart resulting in less blood pumped out to the rest of the body (cardiac output). The purpose of this study is to investigate if changing the volume of the positive pressure ventilation (tidal volume) affects blood flow to the lungs and cardiac output in patients with Fontan circulation.
Interventions
- OTHER Small volume breath and fast breathing rate for 5 minutes
- OTHER Large volume breath and slow breathing rate for 5 minutes
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2021-02-22 |
| Est. Completion | 2022-08-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04633343
The ClinicalTrials.gov registry entry for NCT04633343 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Stanford University, which has 1,744 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Small volume breath and fast breathing rate for 5 minutes is the first listed.
NCT04633343 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04633343 about?
NCT04633343 is a clinical study titled "Effects of Different Tidal Volume Ventilation Strategies on Fontan Flow and Hemodynamics". In patients with Fontan circulation blood is not pumped to the lungs from a ventricle. Instead the superior vena cava and inferior vena cava is connected to the pulmonary artery and blood flow to the lungs occurs passively along this Fontan pathway. This passive blood flow to the lungs occurs best w...
What is the current status of trial NCT04633343?
This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2021-02-22. Estimated completion is 2022-08-30.
What interventions are being tested in trial NCT04633343?
The interventions under investigation include: Small volume breath and fast breathing rate for 5 minutes (OTHER), Large volume breath and slow breathing rate for 5 minutes (OTHER).
Who is sponsoring clinical trial NCT04633343?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
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